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Literature summary extracted from

  • Saini, R.; Patel, S.; Saluja, R.; Sahasrabuddhe, A.A.; Singh, M.P.; Habib, S.; Bajpai, V.K.; Dikshit, M.
    Nitric oxide synthase localization in the rat neutrophils: immunocytochemical, molecular, and biochemical studies (2006), J. Leukoc. Biol., 79, 519-528.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.13.39 cytoplasm isozyme nNOS Rattus norvegicus 5737
-
1.14.13.39 additional information subcellular distribution of NOS and caveolin-1, nNOS and iNOS are co-localized with caveolin-1, overview Rattus norvegicus
-
-
1.14.13.39 nucleus isozyme iNOS Rattus norvegicus 5634
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.14.13.39 Ca2+
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.13.39 2 L-arginine + 3 NADPH + 4 O2 + 3 H+ Rattus norvegicus
-
 2 L-citrulline + 2 NO + 3 NADP+ + 4 H2O
-
 ?
1.14.13.39 additional information Rattus norvegicus caveolin-1 is a prominent NOS-interacting protein in rat polymorphonuclear neutrophils ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.39 Rattus norvegicus
-
 male Sprague-Dawley rats, isozymes nNOS and iNOS
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.39 neutrophil polymorphonuclear neutrophils, PMN Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.39 2 L-arginine + 3 NADPH + 4 O2 + 3 H+
-
 Rattus norvegicus 2 L-citrulline + 2 NO + 3 NADP+ + 4 H2O
-
 ?
1.14.13.39 additional information caveolin-1 is a prominent NOS-interacting protein in rat polymorphonuclear neutrophils Rattus norvegicus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.13.39 nitric oxide synthase
-
 Rattus norvegicus
1.14.13.39 NO synthase
-
 Rattus norvegicus
1.14.13.39 NOS
-
 Rattus norvegicus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.14.13.39 37
-
 assay at Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.14.13.39 7.4
-
 assay at Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.39 Calmodulin
-
 Rattus norvegicus
1.14.13.39 FAD
-
 Rattus norvegicus
1.14.13.39 FMN
-
 Rattus norvegicus
1.14.13.39 NADPH
-
 Rattus norvegicus
1.14.13.39 tetrahydrobiopterin
-
 Rattus norvegicus