EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.7.48 | recombinant NV 3Dpol, as well as a 3Dpol active-site mutant are expressed in Escherichia coli | Norovirus Hu/NLV/Dresden174/pUS-NorII/1997/GE |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.7.48 | Norovirus Hu/NLV/Dresden174/pUS-NorII/1997/GE | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.7.48 | - |
Norovirus Hu/NLV/Dresden174/pUS-NorII/1997/GE |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.48 | nucleoside triphosphate + RNAn | NV 3Dpol yields two different products when incubated with synthetic RNA in vitro: (1) a double-stranded RNA consisting of two single strands of opposite polarity or (2) the single-stranded RNA template labelled at its 39 terminus by terminal transferase activity. Initiation of RNA synthesis by NV 3Dpol on heteromeric RNA template occurs de novo | Norovirus Hu/NLV/Dresden174/pUS-NorII/1997/GE | diphosphate + RNAn+1 | - |
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