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Literature summary extracted from
- Determination of thymidine phosphorylase activity by a non-radiochemical assay using reversed-phase high-performance liquid chromatography (2005), J. Chromatogr. B, 820, 271-275.
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 2.4.2.4 | 0.00064 | - |
phosphate | 37°C, pH 7.4 | Homo sapiens |  |
| 2.4.2.4 | 0.043 | - |
thymidine | 37°C, pH 7.4 | Homo sapiens | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.4.2.4 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 2.4.2.4 | leukocyte | no differences in thymidine phosphorylase activity between man and women or with increasing age | Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 2.4.2.4 | 0.00527 | - |
mean thymidine phosphorylase activity in population | Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.4.2.4 | thymidine + phosphate | - |
Homo sapiens | thymine + 2-deoxy-D-ribose 1-phosphate | - |
? | |
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Release 2023.1 (January 2023)
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