EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.33 | acetyl-CoA | effective inhibitor | Plasmodium falciparum | |
2.7.1.33 | CoA | IC50: 0.2 mM | Plasmodium falciparum | |
2.7.1.33 | coenzyme A | feedback inhibition regulates pantothenol uptake. Furosemide reduces this inherent feedback inhibition by competing with coenzyme A for binding to pantothenate kinase, thereby increasing pantothenol uptake | Plasmodium falciparum | |
2.7.1.33 | malonyl-CoA | effective inhibitor | Plasmodium falciparum |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.33 | Plasmodium falciparum | - |
- |
- |
2.7.1.33 | Plasmodium falciparum | - |
strains 3D7 and FAF6 | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.33 | ATP + (R)-pantothenate | - |
Plasmodium falciparum | ADP + (R)-4'-phosphopantothenate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.33 | PanK | - |
Plasmodium falciparum |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.33 | ATP | - |
Plasmodium falciparum |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
2.7.1.33 | 0.2 | - |
IC50: 0.2 mM | Plasmodium falciparum | CoA |