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Literature summary extracted from

  • Kudo, M.; Canfield, W.M.
    Structural requirements for efficient processing and activation of recombinant human UDP-N-acetylglucosamine:lysosomal-enzyme-N-acetylglucosamine-1-phosphotransferase (2006), J. Biol. Chem., 281, 11761-11768.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.8.17 expressed in CHO-K1 cells Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.8.17 endoplasmic reticulum
-
 Homo sapiens 5783
-
2.7.8.17 Golgi apparatus
-
 Homo sapiens 5794
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.8.17 176000
-
 SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.17 Homo sapiens Q3T906
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.8.17 HPC4-Sepharose column chromatography and DEAE-Sepharose column chromatography Homo sapiens

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.8.17 6.82
-
 after purification Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.17 UDP-N-acetyl-D-glucosamine + methyl-alpha-D-mannoside
-
 Homo sapiens UMP + N-acetyl-D-glucosamine-phospho-(methyl-alpha-D-mannoside)
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.8.17 More multisubunit enzyme with an alpha2beta2gamma2 arrangement Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.7.8.17 GlcNAc-phosphotransferase
-
 Homo sapiens
2.7.8.17 UDP-N-acetylglucosamine:lysosomal-enzyme-N-acetylglucosamine-1-phosphotransferase
-
 Homo sapiens