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Literature summary extracted from

  • Ensenauer, R.; He, M.; Willard, J.M.; Goetzman, E.S.; Corydon, T.J.; Vandahl, B.B.; Mohsen, A.W.; Isaya, G.; Vockley, J.
    Human acyl-CoA dehydrogenase-9 plays a novel role in the mitochondrial beta-oxidation of unsaturated fatty acids (2005), J. Biol. Chem., 280, 32309-32316.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.3.8.7 additional information highly homologous to human very-long-chain acyl-CoA dehydrogenase Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.8.7 expressed in Escherichia coli Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.8.7 0.00007
-
 palmitoleoyl-CoA
-
 Homo sapiens
1.3.8.7 0.00021
-
 linoleoyl-CoA
-
 Homo sapiens
1.3.8.7 0.0008
-
 palmitoyl-CoA
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.8.7 mitochondrial membrane
-
 Homo sapiens 31966
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.3.8.7 119000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.3.8.7 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.8.7 affinity-purified, ca. 95% pure Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.8.7 muscle
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.8.7 (4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-docosahexaenoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 (5Z,8Z,11Z,14Z,17Z) -5,8,11,14,17-icosapentaenoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 2,6-dimethylheptanoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 4,8,12-trimethyltridecanoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 arachidonoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 arachidoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 decanoyl-CoA + electron transfer flavoprotein
-
 Homo sapiens (2E)-2-decenoyl-CoA + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 docosanoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 elaidoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 heptadecanoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 hexanoyl-CoA + electron transfer flavoprotein
-
 Homo sapiens (2E)-2-hexenoyl-CoA + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 lauroyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 linoleoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 myristoleoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 myristoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 nonanoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 octanoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 oleoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 palmitoleoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 palmitoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 pentadecanoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 stearoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 undecanoyl-CoA + oxidized electron transfer flavoprotein
-
 Homo sapiens ? + reduced electron transfer flavoprotein
-
 ?

Subunits

EC Number Subunits Comment Organism
1.3.8.7 dimer gel filtration, 64800, predicted by 37-amino acid leader peptide cleaved sequentially by two mitochondrial peptidases Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
1.3.8.7 ACAD-9
-
 Homo sapiens
1.3.8.7 acyl-CoA dehydrogenase-9
-
 Homo sapiens