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Literature summary extracted from

  • Choi, M.G.; Kurnov, V.; Kersting, M.C.; Sreenivas, A.; Carman, G.M.
    Phosphorylation of the yeast choline kinase by protein kinase C. Identification of Ser25 and Ser30 as major sites of phosphorylation (2005), J. Biol. Chem., 280, 26105-26112.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.32 expressed in Sf9 cells Saccharomyces cerevisiae

Protein Variants

EC Number Protein Variants Comment Organism
2.7.1.32 S25A mutation results in 32% decrease of phosphatidylcholine synthesis compared to the wild type enzyme Saccharomyces cerevisiae
2.7.1.32 S25D mutation results in 14% increase of phosphatidylcholine synthesis compared to the wild type enzyme Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.32 Saccharomyces cerevisiae
-
-
-
2.7.1.32 Saccharomyces cerevisiae KS106
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.32 Con A column chromatography, Affi-Gel Blue gel filtration and Mono Q column chromatography Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.32 ATP + choline
-
 Saccharomyces cerevisiae ADP + O-phosphocholine
-
 ?
2.7.1.32 ATP + choline
-
 Saccharomyces cerevisiae KS106 ADP + O-phosphocholine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.32 ChoK
-
 Saccharomyces cerevisiae

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.32 ATP
-
 Saccharomyces cerevisiae