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Literature summary extracted from
- Activity of human dihydrolipoamide dehydrogenase is largely reduced by mutation at isoleucine-51 to alanine (2006), J. Biochem. Mol. Biol., 39, 223-227.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.8.1.4 | expressed in Escherichia coli | Homo sapiens |
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 1.8.1.4 | I51A | mutant with about 100fold reduced activity compared to the wild type enzyme | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.8.1.4 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.8.1.4 | nickel iminodiacetic acid Sepharose 6B column chromatography | Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.1.4 | dihydrolipoamide + NAD+ | - |
Homo sapiens | lipoamide + NADH + H+ | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.8.1.4 | dihydrolipoamide dehydrogenase | - |
Homo sapiens |
| 1.8.1.4 | dihydrolipoamide:NAD+ oxidoreductase | - |
Homo sapiens |
| 1.8.1.4 | E3 | - |
Homo sapiens |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.8.1.4 | NAD+ | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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