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Literature summary extracted from

  • Candon, H.L.; Allan, B.J.; Fraley, C.D.; Gaynor, E.C.
    Polyphosphate kinase 1 (PPK1) is a pathogenesis determinant in Campylobacter jejuni (2007), J. Bacteriol., 189, 8099-8108.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
2.7.4.1 additional information 50% of the wild type gene are deleted, mutants reveal lower level of phosphorylated products and higher suceptibility to environmental stress Campylobacter jejuni
2.7.4.1 additional information generation of a targeted ppk1 deletion mutant in Campylobacter jejuni strain 81-176, which exhibits low levels of polyphosphate at all growth stages in contrast to the wild-type enzyme. The DELTAppk1 mutant is defective for survival during osmotic shock and low-nutrient stress, phenotype, overview Campylobacter jejuni

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.4.1 Mg2+
-
 Campylobacter jejuni

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.4.1 ATP + (phosphate)n Campylobacter jejuni polyphosphate utilization and accumulation contribute significantly to Campylobacter jejuni pathogenesis and affect its ability to adapt to specific stresses and stringencies ADP + (phosphate)n+1
-
 r
2.7.4.1 ATP + (phosphate)n Campylobacter jejuni 81-176 polyphosphate utilization and accumulation contribute significantly to Campylobacter jejuni pathogenesis and affect its ability to adapt to specific stresses and stringencies ADP + (phosphate)n+1
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.1 Campylobacter jejuni A1W0X7
-
-
2.7.4.1 Campylobacter jejuni A1W0X7 highly invasive strain 81-176
-
2.7.4.1 Campylobacter jejuni 81-176 A1W0X7
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.4.1 additional information wild-type enzyme activity increases significantly as the bacteria transition from log to stationary phase Campylobacter jejuni
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.1 ATP + (phosphate)n
-
 Campylobacter jejuni ADP + (phosphate)n+1
-
 r
2.7.4.1 ATP + (phosphate)n polyphosphate utilization and accumulation contribute significantly to Campylobacter jejuni pathogenesis and affect its ability to adapt to specific stresses and stringencies Campylobacter jejuni ADP + (phosphate)n+1
-
 r
2.7.4.1 ATP + (phosphate)n
-
 Campylobacter jejuni 81-176 ADP + (phosphate)n+1
-
 r
2.7.4.1 ATP + (phosphate)n polyphosphate utilization and accumulation contribute significantly to Campylobacter jejuni pathogenesis and affect its ability to adapt to specific stresses and stringencies Campylobacter jejuni 81-176 ADP + (phosphate)n+1
-
 r

Synonyms

EC Number Synonyms Comment Organism
2.7.4.1 ATP:polyphosphate phosphotransferase
-
 Campylobacter jejuni
2.7.4.1 kinase, polyphosphate (phosphorylating)
-
 Campylobacter jejuni
2.7.4.1 polyphosphate kinase
-
 Campylobacter jejuni
2.7.4.1 polyphosphate kinase 1
-
 Campylobacter jejuni
2.7.4.1 PPK
-
 Campylobacter jejuni
2.7.4.1 PPK1
-
 Campylobacter jejuni

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.4.1 ATP
-
 Campylobacter jejuni