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Literature summary extracted from

  • Yi, H.; Bojja, R.S.; Fu, J.; Du, L.
    Direct evidence for the function of FUM13 in 3-ketoreduction of mycotoxin fumonisins in Fusarium verticillioides (2005), J. Agric. Food Chem., 53, 5456-5460.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.35 gene FUM13, expression of His-tagged enzyme in Escherichia coli, expression in and functional complementation of Saccharomyces cerevisiae 3-ketosphinganine reductase mutant strain tsc10, overview Fusarium verticillioides

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.35 3-oxofumonisin B3 + NADPH Fusarium verticillioides the enzyme is required for biosynthesis of fumonisins fumonisin B3 + NADP+
-
 ?
1.1.1.35 3-oxofumonisin B3 + NADPH Fusarium verticillioides A0149 the enzyme is required for biosynthesis of fumonisins fumonisin B3 + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.35 Fusarium verticillioides
-
 gene FUM13
-
1.1.1.35 Fusarium verticillioides A0149
-
 gene FUM13
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.35 recombinant His-tagged enzyme from Escherichia coli by nickel affinity chromatography Fusarium verticillioides

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.35 3-oxofumonisin B3 + NADPH the enzyme is required for biosynthesis of fumonisins Fusarium verticillioides fumonisin B3 + NADP+
-
 ?
1.1.1.35 3-oxofumonisin B3 + NADPH 3-keto reduction Fusarium verticillioides fumonisin B3 + NADP+
-
 ?
1.1.1.35 3-oxofumonisin B3 + NADPH the enzyme is required for biosynthesis of fumonisins Fusarium verticillioides A0149 fumonisin B3 + NADP+
-
 ?
1.1.1.35 3-oxofumonisin B3 + NADPH 3-keto reduction Fusarium verticillioides A0149 fumonisin B3 + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.35 Fum13p
-
 Fusarium verticillioides

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.1.1.35 37
-
 assay at Fusarium verticillioides

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.35 7.4
-
 assay at Fusarium verticillioides

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.35 NADPH
-
 Fusarium verticillioides