Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Kawai, K.; Watabe, S.; Matsuda, M.; Sakamoto, K.; Kamano, T.
    Correlation between expression of orotate phosphoribosyl transferase and 5-fluorouracil sensitivity, as measured by apoptosis index in colorectal cancer tissue (2005), Int. J. Gastrointest. Cancer, 35, 197-203.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.2.10 5-fluorouracil + 5-phospho-alpha-D-ribose 1-diphosphate Homo sapiens
-
 5-fluorouridine 5'-phosphate + diphosphate
-
 ?
2.4.2.10 additional information Homo sapiens the enzyme expression is weakly correlated to 5-fluorouracil sensitivity and apoptotic cell rate, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.10 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.10 colonic cancer cell colorectal cancer tissue Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.2.10 additional information
-
 enzyme expression rate in tumor tissue with or without treatment with 5-fluorouracil Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.10 5-fluorouracil + 5-phospho-alpha-D-ribose 1-diphosphate
-
 Homo sapiens 5-fluorouridine 5'-phosphate + diphosphate
-
 ?
2.4.2.10 additional information the enzyme expression is weakly correlated to 5-fluorouracil sensitivity and apoptotic cell rate, overview Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.2.10 OPRT
-
 Homo sapiens