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Literature summary extracted from

  • Matsushima, K.; Uda, K.; Ishida, K.; Kokufuta, C.; Iwasaki, N.; Suzuki, T.
    Comparison of kinetic constants of creatine kinase isoforms (2006), Int. J. Biol. Macromol., 38, 83-88.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.3.2 0.2
-
 ATP cytoplasmic isoform M1, 25°C Danio rerio
2.7.3.2 0.31
-
 ATP mitochondrial isoform, 25°C Mus musculus
2.7.3.2 0.35
-
 Creatine mitochondrial isoform, 25°C Mus musculus
2.7.3.2 0.65
-
 ATP cytoplasmic isoform B, 25°C Mus musculus
2.7.3.2 0.7
-
 ATP cytoplasmic isoform M1, 25°C Lethenteron camtschaticum
2.7.3.2 0.75
-
 ATP cytoplasmic isoform M, 25°C Mus musculus
2.7.3.2 0.8
-
 ATP cytoplasmic isoform M1, 25°C Hediste diversicolor
2.7.3.2 0.8
-
 ATP cytoplasmic isoform M2, 25°C Danio rerio
2.7.3.2 0.9
-
 ATP mitochondrial isoform M2, 25°C Hediste diversicolor
2.7.3.2 1
-
 ATP cytoplasmic isoform B, 25°C Danio rerio
2.7.3.2 1
-
 ATP cytoplasmic isoform M2, 25°C Lethenteron camtschaticum
2.7.3.2 1.35
-
 ATP mitochondrial isoform M2, 25°C Dendronephthya gigantea
2.7.3.2 1.5
-
 Creatine cytoplasmic isoform B, 25°C Mus musculus
2.7.3.2 2.7
-
 Creatine cytoplasmic isoform B, 25°C Danio rerio
2.7.3.2 4.7
-
 Creatine cytoplasmic isoform M, 25°C Mus musculus
2.7.3.2 10.8
-
 Creatine cytoplasmic isoform M1, 25°C Hediste diversicolor
2.7.3.2 11.2
-
 Creatine cytoplasmic isoform M2, 25°C Danio rerio
2.7.3.2 14.5
-
 Creatine cytoplasmic isoform M1, 25°C Lethenteron camtschaticum
2.7.3.2 20.2
-
 Creatine mitochondrial isoform M2, 25°C Dendronephthya gigantea
2.7.3.2 23.5
-
 Creatine cytoplasmic isoform M1, 25°C Danio rerio
2.7.3.2 25.5
-
 Creatine mitochondrial isoform M2, 25°C Hediste diversicolor
2.7.3.2 26.4
-
 Creatine cytoplasmic isoform M2, 25°C Lethenteron camtschaticum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.3.2 cytoplasm
-
 Hediste diversicolor 5737
-
2.7.3.2 cytoplasm isoforms M, B Mus musculus 5737
-
2.7.3.2 cytoplasm isoforms M1, M2, B Lethenteron camtschaticum 5737
-
2.7.3.2 cytoplasm isoforms M1, M2, B Danio rerio 5737
-
2.7.3.2 mitochondrion
-
 Mus musculus 5739
-
2.7.3.2 mitochondrion
-
 Hediste diversicolor 5739
-
2.7.3.2 mitochondrion
-
 Dendronephthya gigantea 5739
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.3.2 Danio rerio
-
 recombinant cytoplasmic isoforms M1, M2, and B
-
2.7.3.2 Dendronephthya gigantea
-
 recombinant mitochondrial isoform
-
2.7.3.2 Hediste diversicolor
-
 recombinant cytoplasmic and mitochondrial isoforms
-
2.7.3.2 Lethenteron camtschaticum
-
 recombinant cytoplasmic isoforms M1, M2, and B
-
2.7.3.2 Mus musculus
-
 recombinant cytoplasmic isoforms M, B and mitochondrial isoform
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.3.2 ATP + creatine
-
 Mus musculus ADP + phosphocreatine
-
 ?
2.7.3.2 ATP + creatine
-
 Lethenteron camtschaticum ADP + phosphocreatine
-
 ?
2.7.3.2 ATP + creatine
-
 Danio rerio ADP + phosphocreatine
-
 ?
2.7.3.2 ATP + creatine
-
 Hediste diversicolor ADP + phosphocreatine
-
 ?
2.7.3.2 ATP + creatine
-
 Dendronephthya gigantea ADP + phosphocreatine
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.7.3.2 additional information
-
 additional information comparison of kinetic constants with enzymes from Danio rerio, Lampetra japonica, Neanthes diversicolor, Dendronephthya gigantea Mus musculus
2.7.3.2 additional information
-
 additional information comparison of kinetic constants with enzymes from Mus musculus, Danio rerio, Lampetra japonica, Dendronephthya gigantea Hediste diversicolor
2.7.3.2 additional information
-
 additional information comparison of kinetic constants with enzymes from Mus musculus, Danio rerio, Lampetra japonica, Neanthes diversicolor Dendronephthya gigantea
2.7.3.2 additional information
-
 additional information comparison of kinetic constants with enzymes from Mus musculus, Danio rerio, Neanthes diversicolor, Dendronephthya gigantea Lethenteron camtschaticum
2.7.3.2 additional information
-
 additional information comparison of kinetic constants with enzymes from Mus musculus, Lampetra japonica, Neanthes diversicolor, Dendronephthya gigantea Danio rerio
2.7.3.2 4.5
-
 Creatine mitochondrial isoform, 25°C Mus musculus
2.7.3.2 12.5
-
 Creatine cytoplasmic isoform M2, 25°C Lethenteron camtschaticum
2.7.3.2 13.1
-
 Creatine cytoplasmic isoform B, 25°C Mus musculus
2.7.3.2 14.7
-
 Creatine cytoplasmic isoform M1, 25°C Danio rerio
2.7.3.2 15
-
 Creatine mitochondrial isoform, 25°C Hediste diversicolor
2.7.3.2 16.3
-
 Creatine cytoplasmic isoform M, 25°C Mus musculus
2.7.3.2 19.9
-
 Creatine cytoplasmic isoform M2, 25°C Danio rerio
2.7.3.2 20.3
-
 Creatine cytoplasmic isoform B, 25°C Danio rerio
2.7.3.2 25.2
-
 Creatine cytoplasmic isoform M1, 25°C Lethenteron camtschaticum
2.7.3.2 27.9
-
 Creatine cytoplasmic isoform, 25°C Hediste diversicolor
2.7.3.2 41.3
-
 Creatine mitochondrial isoform, 25°C Dendronephthya gigantea