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Literature summary extracted from

  • Gupta, P.; Gadre, R.
    Increase in NADH-glutamate dehydrogenase activity by mercury in excised bean leaf segments (2005), Indian J. Exp. Biol., 43, 824-828.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.4.1.2 NH4NO3 increases the NADH-GDH activity in the presence of Hg Phaseolus vulgaris

Application

EC Number Application Comment Organism
1.4.1.2 additional information possible role of enzyme under Hg-stress Phaseolus vulgaris

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.1.2 Al3+ inhibits the enzyme activity in the absence of Hg Phaseolus vulgaris
1.4.1.2 glutamine reduces increase in GDH activity due to Hg Phaseolus vulgaris
1.4.1.2 glutathione reduces increase in GDH activity due to Hg Phaseolus vulgaris
1.4.1.2 additional information increase in GDH activity due to Hg remains unaffected by the supply of sucrose Phaseolus vulgaris

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.4.1.2 Al3+ enhances increase in GDH activity due to Hg Phaseolus vulgaris
1.4.1.2 Hg2+ increases NADH-GDH activity substantially, however, specific activity of the enzyme decreases at lower concentration of Hg, and increases to lesser extent at higher concentration of Hg Phaseolus vulgaris

Organism

EC Number Organism UniProt Comment Textmining
1.4.1.2 Phaseolus vulgaris
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.1.2 leaf
-
 Phaseolus vulgaris
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.4.1.2 19.7
-
 in the absence of Hg and in the presence of 0.1 mM AlCl3 Phaseolus vulgaris
1.4.1.2 25
-
 in the presence of 0.001 mM Hg and in the presence of NH4NO3 Phaseolus vulgaris
1.4.1.2 26.7
-
 in the presence of 0.001 mM Hg Phaseolus vulgaris
1.4.1.2 34.2
-
 in the absence of Hg Phaseolus vulgaris
1.4.1.2 52.9
-
 in the absence of Hg and in the presence of 5 mM sucrose Phaseolus vulgaris
1.4.1.2 54.6
-
 in the presence of 0.01 mM Hg Phaseolus vulgaris
1.4.1.2 58.6
-
 in the absence of Hg and in the presence of 5 mM glutathione Phaseolus vulgaris
1.4.1.2 59.4
-
 in the absence of Hg and in the presence of 5 mM glutamine Phaseolus vulgaris
1.4.1.2 65.8
-
 in the absence of Hg and in the presence of NH4NO3 Phaseolus vulgaris
1.4.1.2 70.94
-
 in the presence of 0.1 mM Hg and in the presence of 5 mM glutathione Phaseolus vulgaris
1.4.1.2 72
-
 in the presence of 0.01 mM Hg and in the presence of NH4NO3 Phaseolus vulgaris
1.4.1.2 119.5
-
 in the presence of 0.1 mM Hg Phaseolus vulgaris
1.4.1.2 170.6
-
 in the presence of 0.1 mM Hg and in the presence of 5 mM glutamine Phaseolus vulgaris
1.4.1.2 171.4
-
 in the presence of 0.1 mM Hg and in the presence of 0.1 mM AlCl3 Phaseolus vulgaris
1.4.1.2 243.4
-
 in the presence of 0.1 mM Hg and in the presence of NH4NO3 Phaseolus vulgaris
1.4.1.2 328.2
-
 in the presence of 0.1 mM Hg and in the presence of 5 mM sucrose Phaseolus vulgaris

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.1.2 2-oxoglutarate + NH3 + NADH
-
 Phaseolus vulgaris L-glutamate + H2O + NAD+
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.4.1.2 NADH-GDH
-
 Phaseolus vulgaris
1.4.1.2 NADH-glutamate dehydrogenase
-
 Phaseolus vulgaris

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.1.2 NADH gradual increase in enzyme activity with increasing concentrations of NADH in preparations with 0.1 mM Hg or without Hg Phaseolus vulgaris