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Literature summary extracted from

  • Strasser, P.; Unger, U.; Strobl, B.; Vilas, U.; Vlasak, R.
    Recombinant viral sialate-O-acetylesterases (2004), Glycoconj. J., 20, 551-561.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.53 expressed as GFP-fused secretion protein in Sf9 cells influenza C virus

Protein Variants

EC Number Protein Variants Comment Organism
3.1.1.53 S57T loss of esterase activity influenza C virus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.53 diisopropyl fluorophosphate DFP strong inhibition influenza C virus
3.1.1.53 additional information no inhibition by PMSF influenza C virus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.53 membrane
-
 influenza C virus 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.53 N-acetyl-O-acetylneuraminate + H2O influenza C virus destroys receptors on the surface of the target cells N-acetylneuraminate + acetate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.53 influenza C virus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.1.53 glycoprotein
-
 influenza C virus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.53 9-O-acetyl sialic acid + H2O
-
 influenza C virus sialic acid + acetate
-
 ?
3.1.1.53 bovine submaxillary mucin + H2O
-
 influenza C virus ?
-
 ?
3.1.1.53 additional information incubation of the enzyme with chicken erythrocytes abolishes the agglutinability the erythrocytes influenza C virus ?
-
 ?
3.1.1.53 N-acetyl-O-acetylneuraminate + H2O destroys receptors on the surface of the target cells influenza C virus N-acetylneuraminate + acetate
-
 ?
3.1.1.53 p-nitrophenyl acetate + H2O
-
 influenza C virus p-nitrophenol + acetate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.53 ? two forms with molecular weights of 75000 and 88000 Da detected in SDS-PAGE, the 75000 Da form is assumed to by the unglycosylated precursor of the enzyme influenza C virus

Synonyms

EC Number Synonyms Comment Organism
3.1.1.53 HE
-
 influenza C virus
3.1.1.53 hemagglutinin-esterase
-
 influenza C virus