EC Number | Cloned (Comment) | Organism |
---|---|---|
2.4.3.3 | stable transfection of the breast cancer cell line MDA-MB-231 with ST6GalNAc I cDNA induces sialyl-Tn antigen expression, modifications of the O-glycosylation pattern of a MUC1-related recombinant protein secreted by MDA-MB-231 sialyl-Tn positive cells occurs, sialyl-Tn expression and concomitant changes in the overall O-glycan profiles induce a decrease of adhesion and an increase of migration of MDA-MB-231, overview | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.3.3 | CMP-N-acetylneuraminate + protein MUC1-MFP6 | Homo sapiens | recombinant protein substrate expressed in MDA-MB-231 breast cancer cells, glycoprofiling, overview | ? | - |
? | |
2.4.3.3 | additional information | Homo sapiens | the enzyme participates in the core O-glycan biosynthesis, overview | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.3.3 | Homo sapiens | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.3.3 | CMP-N-acetylneuraminate + protein MUC1-MFP6 | recombinant protein substrate expressed in MDA-MB-231 breast cancer cells, glycoprofiling, overview | Homo sapiens | ? | - |
? | |
2.4.3.3 | CMP-N-acetylneuraminate + protein MUC1-MFP6 | recombinant protein substrate, glycoprofiling, overview | Homo sapiens | ? | - |
? | |
2.4.3.3 | additional information | the enzyme participates in the core O-glycan biosynthesis, overview | Homo sapiens | ? | - |
? | |
2.4.3.3 | additional information | the enzyme transfers a sialic acid residue in alpha-2,6-linkage to the GalNAcalpha1-O-Ser/Thr structure | Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.3.3 | CMP-Neu5Ac: RGalNAcalpha1-O-Ser/Thralpha2,6-sialyltransferase | - |
Homo sapiens |
2.4.3.3 | CMPNeu5Ac:GalNAalpha2,6-sialyltransferase | - |
Homo sapiens |
2.4.3.3 | ST6GalNAc I | - |
Homo sapiens |