EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.4.1.92 | additional information | beta4GalNAcTA null mutant larvae show frequent backward crawling, reductions in nerve terminal bouton number, decreased spontaneous transmitter release frequency, and short, wide, hypercontracted muscles with low calcium content, indicating a role for this enzyme in the neuromuscular system | Drosophila melanogaster |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.244 | UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl-R group | Drosophila sp. (in: flies) | beta4Gal-NAcTA has at least three distinct, tissue-specific roles in neurons and muscles. Substrates are present in both neural and muscle cells that require glycosylation by beta4GalNAcTA for normal function | UDP + N-acetyl-beta-D-galactosaminyl-(1,4)-N-acetyl-beta-D-glucosaminyl-R group | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.92 | Drosophila melanogaster | - |
- |
- |
2.4.1.244 | Drosophila sp. (in: flies) | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.1.92 | larva | - |
Drosophila melanogaster | - |
2.4.1.92 | muscle | - |
Drosophila melanogaster | - |
2.4.1.92 | neuron | - |
Drosophila melanogaster | - |
2.4.1.244 | muscle | beta4Gal-NAcTA has at least three distinct, tissue-specific roles in neurons and muscles. Substrates are present in both neural and muscle cells that require glycosylation by beta4GalNAcTA for normal function | Drosophila sp. (in: flies) | - |
2.4.1.244 | neuron | beta4Gal-NAcTA has at least three distinct, tissue-specific roles in neurons and muscles. Substrates are present in both neural and muscle cells that require glycosylation by beta4GalNAcTA for normal function | Drosophila sp. (in: flies) | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.92 | UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide | - |
Drosophila melanogaster | UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide | - |
? | |
2.4.1.244 | UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl-R group | beta4Gal-NAcTA has at least three distinct, tissue-specific roles in neurons and muscles. Substrates are present in both neural and muscle cells that require glycosylation by beta4GalNAcTA for normal function | Drosophila sp. (in: flies) | UDP + N-acetyl-beta-D-galactosaminyl-(1,4)-N-acetyl-beta-D-glucosaminyl-R group | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.1.92 | beta 1,4-N-acetylgalactosaminyltransferase-A | - |
Drosophila melanogaster |
2.4.1.92 | beta4GalNAcTA | - |
Drosophila melanogaster |