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Literature summary extracted from

  • Maubon, D.; Park, S.; Tanguy, M.; Huerre, M.; Schmitt, C.; Prevost, M.C.; Perlin, D.S.; Latge, J.P.; Beauvais, A.
    AGS3, an a(1-3)glucan synthase gene family member of Aspergillus fumigatus, modulates mycelium growth in the lung of experimentally infected mice (2006), Fungal Genet. Biol., 43, 366-375.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.183 Escherichia coli strain DH5alpha Aspergillus fumigatus

Protein Variants

EC Number Protein Variants Comment Organism
2.4.1.183 additional information deltaags3, with a non-functional, disrupted AGS3 gene. The cell wall composition of the mycelium or the conidia of the deltaags3 mutant and the wild type strain does not present any qualitive or quantitive differences. The dense outer layer surrounding the conidial cell wall that contains melanin is 2times thicker in the deltaags3 mutants than in the wild type. Deletion of AGS1 results in a 2.8 and 1.9fold increase in the expression of AGS1 and AGS2, respectively. Lung invasion in infected mice is significantly higher in the mutant than in the wild type. The mutant has a better resistance to reactive oxygen species and a quicker germination rate Aspergillus fumigatus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.183 Aspergillus fumigatus
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 G10 a spontaneous nitrate reductase mutant of strain CBS 144-89
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Synonyms

EC Number Synonyms Comment Organism
2.4.1.183 AGS3
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 Aspergillus fumigatus
2.4.1.183 AGS3 a gene coding for a putative alpha(1-3)glucan synthase Aspergillus fumigatus