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Literature summary extracted from

  • Manevich, Y.; Fisher, A.B.
    Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism (2005), Free Radic. Biol. Med., 38, 1422-1432.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.11.1.27
-
Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.11.1.27 0.12
-
cumene hydroperoxide
-
Homo sapiens
1.11.1.27 0.12
-
1-palmitoyl-2-linolenoyl-sn-glycero-3-phosphocholine hydroperoxide
-
Homo sapiens
1.11.1.27 0.129
-
1-palmitoyl-2-arichidonoyl-sn-glycero-3-phosphocholine
-
Homo sapiens
1.11.1.27 0.135
-
arachidonoyl hydroperoxide
-
Homo sapiens
1.11.1.27 0.141
-
linolenoyl hydroperoxide
-
Homo sapiens
1.11.1.27 0.142
-
tert-butyl hydroperoxide
-
Homo sapiens
1.11.1.27 0.18
-
H2O2
-
Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.11.1.27 additional information Homo sapiens the enzyme functions in antioxidant defense and lung phospholipid metabolism ?
-
?
1.11.1.27 additional information Mus musculus the enzyme functions in antioxidant defense and lung phospholipid metabolism ?
-
?
1.11.1.27 additional information Rattus norvegicus the enzyme functions in antioxidant defense and lung phospholipid metabolism ?
-
?
1.11.1.27 additional information Bos taurus the enzyme functions in antioxidant defense and lung phospholipid metabolism ?
-
?
1.11.1.27 additional information Sus scrofa the enzyme functions in antioxidant defense and lung phospholipid metabolism ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.27 Bos taurus O77834
-
-
1.11.1.27 Homo sapiens P30041
-
-
1.11.1.27 Mus musculus O08709
-
-
1.11.1.27 Rattus norvegicus O35244
-
-
1.11.1.27 Sus scrofa Q9TSX9
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.11.1.27 lung
-
Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.27 1-palmitoyl-2-arichidonoyl-sn-glycero-3-phosphocholine + GSH
-
Homo sapiens ?
-
?
1.11.1.27 1-palmitoyl-2-linolenoyl-sn-glycero-3-phosphocholine hydroperoxide + GSH
-
Homo sapiens ?
-
?
1.11.1.27 arachidonoyl hydroperoxide + GSH
-
Homo sapiens ?
-
?
1.11.1.27 cumene hydroperoxide + GSH
-
Homo sapiens 2-phenylpropan-2-ol + GSSG
-
?
1.11.1.27 H2O2 + GSH
-
Homo sapiens H2O + GSSG
-
?
1.11.1.27 H2O2 + GSH
-
Mus musculus H2O + GSSG
-
?
1.11.1.27 H2O2 + GSH
-
Rattus norvegicus H2O + GSSG
-
?
1.11.1.27 H2O2 + GSH
-
Bos taurus H2O + GSSG
-
?
1.11.1.27 H2O2 + GSH
-
Sus scrofa H2O + GSSG
-
?
1.11.1.27 linolenoyl hydroperoxide + GSH
-
Homo sapiens ?
-
?
1.11.1.27 additional information the enzyme functions in antioxidant defense and lung phospholipid metabolism Homo sapiens ?
-
?
1.11.1.27 additional information the enzyme functions in antioxidant defense and lung phospholipid metabolism Mus musculus ?
-
?
1.11.1.27 additional information the enzyme functions in antioxidant defense and lung phospholipid metabolism Rattus norvegicus ?
-
?
1.11.1.27 additional information the enzyme functions in antioxidant defense and lung phospholipid metabolism Bos taurus ?
-
?
1.11.1.27 additional information the enzyme functions in antioxidant defense and lung phospholipid metabolism Sus scrofa ?
-
?
1.11.1.27 tert-butyl hydroperoxide + GSH
-
Homo sapiens tert-butanol + GSSG
-
?

Synonyms

EC Number Synonyms Comment Organism
1.11.1.27 peroxiredoxin 6
-
Homo sapiens
1.11.1.27 peroxiredoxin 6
-
Mus musculus
1.11.1.27 peroxiredoxin 6
-
Rattus norvegicus
1.11.1.27 peroxiredoxin 6
-
Bos taurus
1.11.1.27 peroxiredoxin 6
-
Sus scrofa
1.11.1.27 Prdx6
-
Homo sapiens
1.11.1.27 Prdx6
-
Mus musculus
1.11.1.27 Prdx6
-
Rattus norvegicus
1.11.1.27 Prdx6
-
Bos taurus
1.11.1.27 Prdx6
-
Sus scrofa