EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.1.3.14 | additional information | Homo sapiens | biosynthesis of sialic acids | ? | - |
? | |
5.1.3.14 | additional information | Mus musculus | biosynthesis of sialic acids | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.60 | Homo sapiens | Q9Y223 | - |
- |
2.7.1.60 | Homo sapiens | Q9Y223 | isoform 2; bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, isoform GNE2 | - |
2.7.1.60 | Homo sapiens | Q9Y223 | isoform 3; bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, isoform GNE3 | - |
5.1.3.14 | Homo sapiens | Q9Y223 | isoform 2 | - |
5.1.3.14 | Homo sapiens | Q9Y223 | isoform 3 | - |
5.1.3.14 | Mus musculus | Q3UW64 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.1.60 | brain | - |
Homo sapiens | - |
2.7.1.60 | colon | - |
Homo sapiens | - |
2.7.1.60 | kidney | - |
Homo sapiens | - |
2.7.1.60 | liver | - |
Homo sapiens | - |
2.7.1.60 | lung | - |
Homo sapiens | - |
2.7.1.60 | pancreas | - |
Homo sapiens | - |
2.7.1.60 | placenta | - |
Homo sapiens | - |
5.1.3.14 | brain | - |
Homo sapiens | - |
5.1.3.14 | brain | - |
Mus musculus | - |
5.1.3.14 | colon | - |
Homo sapiens | - |
5.1.3.14 | colon | - |
Mus musculus | - |
5.1.3.14 | kidney | - |
Homo sapiens | - |
5.1.3.14 | kidney | - |
Mus musculus | - |
5.1.3.14 | liver | - |
Homo sapiens | - |
5.1.3.14 | liver | - |
Mus musculus | - |
5.1.3.14 | lung | - |
Homo sapiens | - |
5.1.3.14 | pancreas | - |
Homo sapiens | - |
5.1.3.14 | placenta | - |
Homo sapiens | - |
5.1.3.14 | skeletal muscle | - |
Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.60 | ATP + N-acetyl-D-mannosamine | - |
Homo sapiens | ADP + N-acetyl-D-mannosamine 6-phosphate | - |
? | |
2.7.1.60 | additional information | isoform GNE2 displays an extended N-terminus compared with isoform GNE, which is linked directly to the epimerase domain. Recombinant GNE2 still possesses both enzymatic activities of GNE | Homo sapiens | ? | - |
? | |
2.7.1.60 | additional information | isoform GNE3 displays an deleted N-terminus compared with isoform GNE. Recombinant GNE3 shows a total loss of the epimerase activity | Homo sapiens | ? | - |
? | |
5.1.3.14 | additional information | biosynthesis of sialic acids | Homo sapiens | ? | - |
? | |
5.1.3.14 | additional information | biosynthesis of sialic acids | Mus musculus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.60 | GNE2 | enzyme isoform possessing extended N-terminus | Homo sapiens |
2.7.1.60 | GNE3 | enzyme isoform possessing deleted N-terminus | Homo sapiens |
2.7.1.60 | UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase | - |
Homo sapiens |
5.1.3.14 | GNE1 | - |
Homo sapiens |
5.1.3.14 | GNE1 | - |
Mus musculus |
5.1.3.14 | GNE2 | - |
Homo sapiens |
5.1.3.14 | UDP-GlcNAc 2-epimerase | - |
Homo sapiens |
5.1.3.14 | UDP-GlcNAc 2-epimerase | - |
Mus musculus |
5.1.3.14 | UDP-N-acetylglucosamine 2-epimerase | - |
Homo sapiens |
5.1.3.14 | UDP-N-acetylglucosamine 2-epimerase | - |
Mus musculus |