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Literature summary extracted from

  • Fraga, H.; Fernandes, D.; Fontes, R.; Esteves da Silva, J.C.
    Coenzyme A affects firefly luciferase luminescence because it acts as a substrate and not as an allosteric effector (2005), FEBS J., 272, 5206-5216.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.12.7 dehydroluciferyl adenylate IC50: 6 nM Photinus pyralis
1.13.12.7 dehydroluciferyl-CoA IC50: 0.005 mM Photinus pyralis

Organism

EC Number Organism UniProt Comment Textmining
1.13.12.7 Photinus pyralis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.12.7 D-luciferin + O2 + ATP
-
 Photinus pyralis oxidized D-luciferin + CO2 + H2O + AMP + diphosphate + hv
-
 ?
1.13.12.7 dehydroluciferyladenylate + CoA
-
 Photinus pyralis dehydroluciferyl-CoA + ?
-
 ?
1.13.12.7 luciferyl adenylate + O2
-
 Photinus pyralis dehydroluciferyl adenylate + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.13.12.7 firefly luciferase
-
 Photinus pyralis
1.13.12.7 Luc
-
 Photinus pyralis

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.13.12.7 0.000006
-
 IC50: 6 nM Photinus pyralis dehydroluciferyl adenylate
1.13.12.7 0.005
-
 IC50: 0.005 mM Photinus pyralis dehydroluciferyl-CoA