Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Witczak, C.A.; Fujii, N.; Hirshman, M.F.; Goodyear, L.J.
    Ca2+/calmodulin-dependent protein kinase kinase-alpha regulates skeletal muscle glucose uptake independent of AMP-activated protein kinase and Akt activation (2007), Diabetes, 56, 1403-1409.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.17 Calmodulin required Mus musculus
2.7.11.17 additional information CaMKI is phosphorylated at Thr177 and Thr180 by the Ca2+/calmodulin-dependent protein kinase kinase, CaMKKalpha, activating CaMKI, CaMKKK also activates CaMKIV Mus musculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.17 Ca2+ required Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.17 Mus musculus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.11.17 phosphoprotein CaMKI is phosphorylated at Thr177 and Thr180 by the Ca2+/calmodulin-dependent protein kinase kinase, CaMKKalpha, activating CaMKI, CaMKIV is also a substrate for CaMKKK Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.17 skeletal muscle expression of CaMKI isozymes alpha, beta, and delta, not of CaMKIV Mus musculus
-

Synonyms

EC Number Synonyms Comment Organism
2.7.11.17 CaMKI
-
 Mus musculus
2.7.11.17 CaMKIV
-
 Mus musculus