Literature summary extracted from

Hubbard, S.R.; Miller, W.T.
Receptor tyrosine kinases: mechanisms of activation and signaling (2007), Curr. Opin. Cell Biol., 19, 117-123.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.10.1	herceptin	-	Homo sapiens
2.7.10.1	PD168393	-	Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.7.10.1	ATP + a [protein]-L-tyrosine	Homo sapiens	-	ADP + a [protein]-L-tyrosine phosphate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.10.1	Drosophila melanogaster	-	-	-
2.7.10.1	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.10.1	breast carcinoma cell	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.10.1	ATP + a [protein]-L-tyrosine	-	Homo sapiens	ADP + a [protein]-L-tyrosine phosphate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.10.1	ErbB2	-	Homo sapiens
2.7.10.1	ERK	-	Drosophila melanogaster
2.7.10.1	receptor tyrosine kinase	-	Homo sapiens
2.7.10.1	RTK	-	Homo sapiens

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.7.10.1	ATP	-	Homo sapiens

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Release 2023.1 (January 2023)