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Literature summary extracted from

  • Campos, J.M.; Sanchez-Martin, R.M.; Conejo-Garcia, A.; Entrena, A.; Gallo, M.A.; Espinosa, A.
    (Q)SAR studies to design new human choline kinase inhibitors as antiproliferative drugs (2006), Curr. Med. Chem., 13, 1231-1248.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.32 1,1'-(benzene-1,3-diyldimethanediyl)bis(4-piperidin-1-ylpyridinium) dibromide IC50: 0.0528 mM Homo sapiens
2.7.1.32 1,1'-(benzene-1,3-diyldimethanediyl)bis(4-pyrrolidin-1-ylpyridinium) dibromide IC50: 0.0842 mM Homo sapiens
2.7.1.32 1,1'-(benzene-1,3-diyldimethanediyl)bis(4-[[(3,5-dichlorophenyl)amino]methyl]pyridinium) dibromide IC50: 0.0084 mM Homo sapiens
2.7.1.32 1,1'-(benzene-1,3-diyldimethanediyl)bis(4-[[(4-chlorophenyl)amino]methyl]pyridinium) dibromide IC50: 0.0072 mM Homo sapiens
2.7.1.32 1,1'-(benzene-1,3-diyldimethanediyl)bis[4-[(phenylamino)methyl]pyridinium] dibromide IC50: 0.0375 mM Homo sapiens
2.7.1.32 1,1'-(benzene-1,4-diyldimethanediyl)bis(4-piperidin-1-ylpyridinium) dibromide IC50: 0.0377 mM Homo sapiens
2.7.1.32 1,1'-(benzene-1,4-diyldimethanediyl)bis(4-pyrrolidin-1-ylpyridinium) dibromide IC50: 0.024 mM Homo sapiens
2.7.1.32 1,1'-(benzene-1,4-diyldimethanediyl)bis(4-[[(3,5-dichlorophenyl)amino]methyl]pyridinium) dibromide IC50: 0.0097 mM Homo sapiens
2.7.1.32 1,1'-(benzene-1,4-diyldimethanediyl)bis(4-[[(4-chlorophenyl)amino]methyl]pyridinium) dibromide IC50: 0.0029 mM Homo sapiens
2.7.1.32 1,1'-(benzene-1,4-diyldimethanediyl)bis[4-[(phenylamino)methyl]pyridinium] dibromide IC50: 0.015 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-amino-3-methylquinolinium) dibromide IC50: 0.0119 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-amino-7-chloroquinolinium) dibromide IC50: 0.0206 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-aminoquinolinium) dibromide IC50: 0.0012 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-azepan-1-ylquinolinium) dibromide IC50: 0.0005 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-piperidin-1-ylpyridinium) dibromide IC50: 0.0019 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-pyrrolidin-1-ylpyridinium) dibromide IC50: 0.0058 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-[[(3,5-dichlorophenyl)amino]methyl]pyridinium) dibromide IC50: 0.0026 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-[[(4-chlorophenyl)amino]methyl]pyridinium) dibromide IC50: 0.0015 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-[[(4-chlorophenyl)amino]methyl]quinolinium) dibromide IC50: 0.0021 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(7-amino-4-[[(4-chlorophenyl)amino]methyl]-8-methylquinolinium) dibromide IC50: 0.147 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(7-chloro-4-pyrrolidin-1-ylquinolinium) dibromide IC50: 0.0012 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(7-chloro-4-[[(4-chlorophenyl)amino]methyl]quinolinium) dibromide IC50: 0.0057 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis[4-(dimethylamino)quinolinium] dibromide IC50: 0.0044 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis[4-(phenylamino)quinolinium] dibromide IC50: 0.0013 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis[4-[(phenylamino)methyl]pyridinium] dibromide IC50: 0.00043 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis[4-[(phenylamino)methyl]quinolinium] dibromide IC50: 0.0004 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis[7-amino-8-methyl-4-[(phenylamino)methyl]quinolinium] dibromide IC50: 0.0568 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis[7-chloro-4-(dimethylamino)quinolinium] dibromide IC50: 0.0096 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis[7-chloro-4-[(phenylamino)methyl]quinolinium] dibromide IC50: 0.0031 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-amino-3-methylquinolinium) dibromide IC50: above 0.2 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-amino-7-chloroquinolinium) dibromide IC50: 0.0633 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-aminoquinolinium) dibromide IC50: 0.0811 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-azepan-1-ylquinolinium) dibromide IC50: 0.0022 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-piperidin-1-ylpyridinium) dibromide IC50: 0.0088 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-pyrrolidin-1-ylpyridinium) dibromide IC50: 0.0111 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-[[(3,5-dichlorophenyl)amino]methyl]pyridinium) dibromide IC50: 0.0034 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-[[(4-chlorophenyl)amino]methyl]pyridinium) dibromide IC50: 0.0018 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-[[(4-chlorophenyl)amino]methyl]quinolinium) dibromide IC50: 0.002 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(7-amino-4-[[(4-chlorophenyl)amino]methyl]-8-methylquinolinium) dibromide IC50: 0.0461 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(7-chloro-4-pyrrolidin-1-ylquinolinium) dibromide IC50: 0.0198 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(7-chloro-4-[[(4-chlorophenyl)amino]methyl]quinolinium) dibromide IC50: 0.0114 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis[4-(dimethylamino)quinolinium] dibromide IC50: 0.0397 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis[4-(phenylamino)quinolinium] dibromide IC50: 0.0178 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis[4-[(phenylamino)methyl]pyridinium] dibromide IC50: 0.0043 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis[4-[(phenylamino)methyl]quinolinium] dibromide IC50: 0.003 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis[7-amino-8-methyl-4-[(phenylamino)methyl]quinolinium] dibromide IC50: 0.0961 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis[7-chloro-4-(dimethylamino)quinolinium] dibromide IC50: 0.0206 mM Homo sapiens
2.7.1.32 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis[7-chloro-4-[(phenylamino)methyl]quinolinium] dibromide IC50: 0.0114 mM Homo sapiens
2.7.1.32 1,1'-[(1S,2S)-cyclopropane-1,2-diyldiethane-2,1-diyl]bis(4-piperidin-1-ylpyridinium) dibromide IC50: 0.098 mM Homo sapiens
2.7.1.32 1,1'-[(1S,2S)-cyclopropane-1,2-diyldiethane-2,1-diyl]bis(4-pyrrolidin-1-ylpyridinium) dibromide IC50: above 0.1 mM Homo sapiens
2.7.1.32 1,1'-[(1S,2S)-cyclopropane-1,2-diyldiethane-2,1-diyl]bis(4-[[(3,5-dichlorophenyl)amino]methyl]pyridinium) dibromide IC50: 0.0482 mM; IC50: above 0.1 mM Homo sapiens
2.7.1.32 1,1'-[(1S,2S)-cyclopropane-1,2-diyldiethane-2,1-diyl]bis[4-[(phenylamino)methyl]pyridinium] dibromide IC50: above 0.1 mM Homo sapiens
2.7.1.32 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis(4-amino-7-chloroquinolinium) dibromide IC50: above 0.2 mM Homo sapiens
2.7.1.32 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis(4-aminoquinolinium) dibromide IC50: 0.08 mM Homo sapiens
2.7.1.32 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis(4-azepan-1-ylquinolinium) dibromide IC50: 0.006 mM Homo sapiens
2.7.1.32 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis(4-[[(4-chlorophenyl)amino]methyl]quinolinium) dibromide IC50: 0.0048 mM Homo sapiens
2.7.1.32 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis(7-amino-4-[[(4-chlorophenyl)amino]methyl]-8-methylquinolinium) dibromide IC50: 0.0575 mM Homo sapiens
2.7.1.32 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis(7-chloro-4-pyrrolidin-1-ylquinolinium) dibromide IC50: 0.001 mM Homo sapiens
2.7.1.32 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis(7-chloro-4-[[(4-chlorophenyl)amino]methyl]quinolinium) dibromide IC50: 0.0057 mM Homo sapiens
2.7.1.32 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis[4-(dimethylamino)quinolinium] dibromide IC50: 0.0102 mM Homo sapiens
2.7.1.32 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis[4-(phenylamino)quinolinium] dibromide IC50: 0.0023 mM Homo sapiens
2.7.1.32 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis[4-[(phenylamino)methyl]quinolinium] dibromide IC50: 0.0014 mM Homo sapiens
2.7.1.32 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis[7-amino-8-methyl-4-[(phenylamino)methyl]quinolinium] dibromide IC50: 0.133 mM Homo sapiens
2.7.1.32 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis[7-chloro-4-(dimethylamino)quinolinium] dibromide IC50: 0.009 mM Homo sapiens
2.7.1.32 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis[7-chloro-4-[(phenylamino)methyl]quinolinium] dibromide IC50: 0.0035 mM Homo sapiens
2.7.1.32 12,19-diaza-1,8-diazoniapentacyclo[18.2.2.23,6.28,11.214,17]triaconta-1(22),3,5,8,10,14,16,20,23,25,27,29-dodecaene dibromide IC50: 0.0132 mM Homo sapiens
2.7.1.32 12,21-diaza-1,8-diazoniapentacyclo[20.2.2.23,6.28,11.014,19]triaconta-1(24),3,5,8,10,14,16,18,22,25,27,29-dodecaene dibromide IC50: 0.0021 mM Homo sapiens
2.7.1.32 14,21-diaza-1,10-diazoniapentacyclo[20.2.2.210,13.216,19.03,8]triaconta-1(24),3,5,7,10,12,16,18,22,25,27,29-dodecaene dibromide IC50: 0.0003 mM Homo sapiens
2.7.1.32 4-chloro-N-methylanilino IC50: 0.0014 mM Homo sapiens
2.7.1.32 5,10,11,16,17,22-hexahydro-6,9:18,21-diethenodibenzo[g,p][1,5,10,14]tetraazacyclooctadecine-6,21-diium dibromide IC50: 0.0248 mM Homo sapiens
2.7.1.32 hemicholinium-3
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.32 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.32 ATP + choline
-
 Homo sapiens ADP + O-phosphocholine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.32 ChoK
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.32 ATP
-
 Homo sapiens

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.7.1.32 0.0003
-
 IC50: 0.0003 mM Homo sapiens 14,21-diaza-1,10-diazoniapentacyclo[20.2.2.210,13.216,19.03,8]triaconta-1(24),3,5,7,10,12,16,18,22,25,27,29-dodecaene dibromide
2.7.1.32 0.0004
-
 IC50: 0.0004 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis[4-[(phenylamino)methyl]quinolinium] dibromide
2.7.1.32 0.00043
-
 IC50: 0.00043 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis[4-[(phenylamino)methyl]pyridinium] dibromide
2.7.1.32 0.0005
-
 IC50: 0.0005 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-azepan-1-ylquinolinium) dibromide
2.7.1.32 0.001
-
 IC50: 0.001 mM Homo sapiens 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis(7-chloro-4-pyrrolidin-1-ylquinolinium) dibromide
2.7.1.32 0.0012
-
 IC50: 0.0012 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-aminoquinolinium) dibromide
2.7.1.32 0.0012
-
 IC50: 0.0012 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(7-chloro-4-pyrrolidin-1-ylquinolinium) dibromide
2.7.1.32 0.0013
-
 IC50: 0.0013 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis[4-(phenylamino)quinolinium] dibromide
2.7.1.32 0.0014
-
 IC50: 0.0014 mM Homo sapiens 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis[4-[(phenylamino)methyl]quinolinium] dibromide
2.7.1.32 0.0014
-
 IC50: 0.0014 mM Homo sapiens 4-chloro-N-methylanilino
2.7.1.32 0.0015
-
 IC50: 0.0015 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-[[(4-chlorophenyl)amino]methyl]pyridinium) dibromide
2.7.1.32 0.0018
-
 IC50: 0.0018 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-[[(4-chlorophenyl)amino]methyl]pyridinium) dibromide
2.7.1.32 0.0019
-
 IC50: 0.0019 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-piperidin-1-ylpyridinium) dibromide
2.7.1.32 0.002
-
 IC50: 0.002 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-[[(4-chlorophenyl)amino]methyl]quinolinium) dibromide
2.7.1.32 0.0021
-
 IC50: 0.0021 mM Homo sapiens 12,21-diaza-1,8-diazoniapentacyclo[20.2.2.23,6.28,11.014,19]triaconta-1(24),3,5,8,10,14,16,18,22,25,27,29-dodecaene dibromide
2.7.1.32 0.0021
-
 IC50: 0.0021 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-[[(4-chlorophenyl)amino]methyl]quinolinium) dibromide
2.7.1.32 0.0022
-
 IC50: 0.0022 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-azepan-1-ylquinolinium) dibromide
2.7.1.32 0.0023
-
 IC50: 0.0023 mM Homo sapiens 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis[4-(phenylamino)quinolinium] dibromide
2.7.1.32 0.0026
-
 IC50: 0.0026 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-[[(3,5-dichlorophenyl)amino]methyl]pyridinium) dibromide
2.7.1.32 0.0029
-
 IC50: 0.0029 mM Homo sapiens 1,1'-(benzene-1,4-diyldimethanediyl)bis(4-[[(4-chlorophenyl)amino]methyl]pyridinium) dibromide
2.7.1.32 0.003
-
 IC50: 0.003 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis[4-[(phenylamino)methyl]quinolinium] dibromide
2.7.1.32 0.0031
-
 IC50: 0.0031 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis[7-chloro-4-[(phenylamino)methyl]quinolinium] dibromide
2.7.1.32 0.0034
-
 IC50: 0.0034 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-[[(3,5-dichlorophenyl)amino]methyl]pyridinium) dibromide
2.7.1.32 0.0035
-
 IC50: 0.0035 mM Homo sapiens 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis[7-chloro-4-[(phenylamino)methyl]quinolinium] dibromide
2.7.1.32 0.0043
-
 IC50: 0.0043 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis[4-[(phenylamino)methyl]pyridinium] dibromide
2.7.1.32 0.0044
-
 IC50: 0.0044 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis[4-(dimethylamino)quinolinium] dibromide
2.7.1.32 0.0048
-
 IC50: 0.0048 mM Homo sapiens 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis(4-[[(4-chlorophenyl)amino]methyl]quinolinium) dibromide
2.7.1.32 0.0057
-
 IC50: 0.0057 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(7-chloro-4-[[(4-chlorophenyl)amino]methyl]quinolinium) dibromide
2.7.1.32 0.0057
-
 IC50: 0.0057 mM Homo sapiens 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis(7-chloro-4-[[(4-chlorophenyl)amino]methyl]quinolinium) dibromide
2.7.1.32 0.0058
-
 IC50: 0.0058 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-pyrrolidin-1-ylpyridinium) dibromide
2.7.1.32 0.006
-
 IC50: 0.006 mM Homo sapiens 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis(4-azepan-1-ylquinolinium) dibromide
2.7.1.32 0.0072
-
 IC50: 0.0072 mM Homo sapiens 1,1'-(benzene-1,3-diyldimethanediyl)bis(4-[[(4-chlorophenyl)amino]methyl]pyridinium) dibromide
2.7.1.32 0.0084
-
 IC50: 0.0084 mM Homo sapiens 1,1'-(benzene-1,3-diyldimethanediyl)bis(4-[[(3,5-dichlorophenyl)amino]methyl]pyridinium) dibromide
2.7.1.32 0.0088
-
 IC50: 0.0088 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-piperidin-1-ylpyridinium) dibromide
2.7.1.32 0.009
-
 IC50: 0.009 mM Homo sapiens 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis[7-chloro-4-(dimethylamino)quinolinium] dibromide
2.7.1.32 0.0096
-
 IC50: 0.0096 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis[7-chloro-4-(dimethylamino)quinolinium] dibromide
2.7.1.32 0.0097
-
 IC50: 0.0097 mM Homo sapiens 1,1'-(benzene-1,4-diyldimethanediyl)bis(4-[[(3,5-dichlorophenyl)amino]methyl]pyridinium) dibromide
2.7.1.32 0.0102
-
 IC50: 0.0102 mM Homo sapiens 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis[4-(dimethylamino)quinolinium] dibromide
2.7.1.32 0.0111
-
 IC50: 0.0111 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-pyrrolidin-1-ylpyridinium) dibromide
2.7.1.32 0.0114
-
 IC50: 0.0114 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis[7-chloro-4-[(phenylamino)methyl]quinolinium] dibromide
2.7.1.32 0.0114
-
 IC50: 0.0114 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(7-chloro-4-[[(4-chlorophenyl)amino]methyl]quinolinium) dibromide
2.7.1.32 0.0119
-
 IC50: 0.0119 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-amino-3-methylquinolinium) dibromide
2.7.1.32 0.0132
-
 IC50: 0.0132 mM Homo sapiens 12,19-diaza-1,8-diazoniapentacyclo[18.2.2.23,6.28,11.214,17]triaconta-1(22),3,5,8,10,14,16,20,23,25,27,29-dodecaene dibromide
2.7.1.32 0.015
-
 IC50: 0.015 mM Homo sapiens 1,1'-(benzene-1,4-diyldimethanediyl)bis[4-[(phenylamino)methyl]pyridinium] dibromide
2.7.1.32 0.0178
-
 IC50: 0.0178 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis[4-(phenylamino)quinolinium] dibromide
2.7.1.32 0.0198
-
 IC50: 0.0198 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(7-chloro-4-pyrrolidin-1-ylquinolinium) dibromide
2.7.1.32 0.0206
-
 IC50: 0.0206 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(4-amino-7-chloroquinolinium) dibromide
2.7.1.32 0.0206
-
 IC50: 0.0206 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis[7-chloro-4-(dimethylamino)quinolinium] dibromide
2.7.1.32 0.024
-
 IC50: 0.024 mM Homo sapiens 1,1'-(benzene-1,4-diyldimethanediyl)bis(4-pyrrolidin-1-ylpyridinium) dibromide
2.7.1.32 0.0248
-
 IC50: 0.0248 mM Homo sapiens 5,10,11,16,17,22-hexahydro-6,9:18,21-diethenodibenzo[g,p][1,5,10,14]tetraazacyclooctadecine-6,21-diium dibromide
2.7.1.32 0.0375
-
 IC50: 0.0375 mM Homo sapiens 1,1'-(benzene-1,3-diyldimethanediyl)bis[4-[(phenylamino)methyl]pyridinium] dibromide
2.7.1.32 0.0377
-
 IC50: 0.0377 mM Homo sapiens 1,1'-(benzene-1,4-diyldimethanediyl)bis(4-piperidin-1-ylpyridinium) dibromide
2.7.1.32 0.0397
-
 IC50: 0.0397 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis[4-(dimethylamino)quinolinium] dibromide
2.7.1.32 0.0461
-
 IC50: 0.0461 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(7-amino-4-[[(4-chlorophenyl)amino]methyl]-8-methylquinolinium) dibromide
2.7.1.32 0.0482
-
 IC50: 0.0482 mM Homo sapiens 1,1'-[(1S,2S)-cyclopropane-1,2-diyldiethane-2,1-diyl]bis(4-[[(3,5-dichlorophenyl)amino]methyl]pyridinium) dibromide
2.7.1.32 0.0528
-
 IC50: 0.0528 mM Homo sapiens 1,1'-(benzene-1,3-diyldimethanediyl)bis(4-piperidin-1-ylpyridinium) dibromide
2.7.1.32 0.0568
-
 IC50: 0.0568 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis[7-amino-8-methyl-4-[(phenylamino)methyl]quinolinium] dibromide
2.7.1.32 0.0575
-
 IC50: 0.0575 mM Homo sapiens 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis(7-amino-4-[[(4-chlorophenyl)amino]methyl]-8-methylquinolinium) dibromide
2.7.1.32 0.0633
-
 IC50: 0.0633 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-amino-7-chloroquinolinium) dibromide
2.7.1.32 0.08
-
 IC50: 0.08 mM Homo sapiens 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis(4-aminoquinolinium) dibromide
2.7.1.32 0.0811
-
 IC50: 0.0811 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-aminoquinolinium) dibromide
2.7.1.32 0.0842
-
 IC50: 0.0842 mM Homo sapiens 1,1'-(benzene-1,3-diyldimethanediyl)bis(4-pyrrolidin-1-ylpyridinium) dibromide
2.7.1.32 0.0961
-
 IC50: 0.0961 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis[7-amino-8-methyl-4-[(phenylamino)methyl]quinolinium] dibromide
2.7.1.32 0.098
-
 IC50: 0.098 mM Homo sapiens 1,1'-[(1S,2S)-cyclopropane-1,2-diyldiethane-2,1-diyl]bis(4-piperidin-1-ylpyridinium) dibromide
2.7.1.32 0.1
-
 IC50: above 0.1 mM Homo sapiens 1,1'-[(1S,2S)-cyclopropane-1,2-diyldiethane-2,1-diyl]bis(4-[[(3,5-dichlorophenyl)amino]methyl]pyridinium) dibromide
2.7.1.32 0.1
-
 IC50: above 0.1 mM Homo sapiens 1,1'-[(1S,2S)-cyclopropane-1,2-diyldiethane-2,1-diyl]bis(4-pyrrolidin-1-ylpyridinium) dibromide
2.7.1.32 0.1
-
 IC50: above 0.1 mM Homo sapiens 1,1'-[(1S,2S)-cyclopropane-1,2-diyldiethane-2,1-diyl]bis[4-[(phenylamino)methyl]pyridinium] dibromide
2.7.1.32 0.133
-
 IC50: 0.133 mM Homo sapiens 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis[7-amino-8-methyl-4-[(phenylamino)methyl]quinolinium] dibromide
2.7.1.32 0.147
-
 IC50: 0.147 mM Homo sapiens 1,1'-(biphenyl-3,3'-diyldimethanediyl)bis(7-amino-4-[[(4-chlorophenyl)amino]methyl]-8-methylquinolinium) dibromide
2.7.1.32 0.2
-
 IC50: above 0.2 mM Homo sapiens 1,1'-(biphenyl-4,4'-diyldimethanediyl)bis(4-amino-3-methylquinolinium) dibromide
2.7.1.32 0.2
-
 IC50: above 0.2 mM Homo sapiens 1,1'-[ethane-1,2-diylbis(benzene-4,1-diylmethanediyl)]bis(4-amino-7-chloroquinolinium) dibromide