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Literature summary extracted from

  • Wu, M.; Zhou, X.J.; Konno, R.; Wang, Y.X.
    D-dopa is unidirectionally converted to L-dopa by D-amino acid oxidase, followed by dopa transaminase (2006), Clin. Exp. Pharmacol. Physiol., 33, 1042-1046.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.3 Sodium benzoate
-
 Rattus norvegicus
2.6.1.49 carbidopa 0.75 mM, significant decrease of activity Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.4.3.3 D-3,4-dihydroxyphenylalanine + H2O + O2 Rattus norvegicus D-Dopa undergoes unidirectional chiral inversion and further suggest that D-Dopa is first oxidatively deaminated by DAAO to its alpha-keto acid and then transaminated by dopa transaminase to L-Dopa ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.3 Rattus norvegicus
-
-
-
2.6.1.49 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.3 kidney
-
 Rattus norvegicus
-
2.6.1.49 kidney
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.3 D-3,4-dihydroxyphenylalanine + H2O + O2 i.e. D-Dopa Rattus norvegicus ?
-
 ?
1.4.3.3 D-3,4-dihydroxyphenylalanine + H2O + O2 D-Dopa undergoes unidirectional chiral inversion and further suggest that D-Dopa is first oxidatively deaminated by DAAO to its alpha-keto acid and then transaminated by dopa transaminase to L-Dopa Rattus norvegicus ?
-
 ?
2.6.1.49 3-(3,4-dihydroxyphenyl)-L-alanine + oxaloacetic acid
-
 Rattus norvegicus 3-(3,4-dihydroxyphenyl)pyruvate + L-aspartate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.3 DAAO
-
 Rattus norvegicus
2.6.1.49 dopa transaminase
-
 Rattus norvegicus