EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.4.3.13 | collagen + H2O + O2 | Homo sapiens | the enzyme initiates the enzymatic stage of collagen and elastin cross-linking. Lysyl oxidase activity is essential for the integrity maintenance of the dermis and for the homeostasis of the epidermis. The LOX protein plays a role in the skin carcinomas and invasion but not through its enzymatic activity | allysyl-collagen + NH3 + H2O2 | - |
? | |
1.4.3.13 | elastin + H2O + O2 | Homo sapiens | the enzyme initiates the enzymatic stage of collagen and elastin cross-linking. Lysyl oxidase activity is essential for the integrity maintenance of the dermis and for the homeostasis of the epidermis. The LOX protein plays a role in the skin carcinomas and invasion but not through its enzymatic activity | allysyl-elastin + NH3 + H2O2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.4.3.13 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.4.3.13 | basal cell carcinoma cell | - |
Homo sapiens | - |
1.4.3.13 | dermis | - |
Homo sapiens | - |
1.4.3.13 | epidermis | - |
Homo sapiens | - |
1.4.3.13 | skin | - |
Homo sapiens | - |
1.4.3.13 | squamous cell carcinoma cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.4.3.13 | collagen + H2O + O2 | the enzyme initiates the enzymatic stage of collagen and elastin cross-linking. Lysyl oxidase activity is essential for the integrity maintenance of the dermis and for the homeostasis of the epidermis. The LOX protein plays a role in the skin carcinomas and invasion but not through its enzymatic activity | Homo sapiens | allysyl-collagen + NH3 + H2O2 | - |
? | |
1.4.3.13 | elastin + H2O + O2 | the enzyme initiates the enzymatic stage of collagen and elastin cross-linking. Lysyl oxidase activity is essential for the integrity maintenance of the dermis and for the homeostasis of the epidermis. The LOX protein plays a role in the skin carcinomas and invasion but not through its enzymatic activity | Homo sapiens | allysyl-elastin + NH3 + H2O2 | - |
? |