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Literature summary extracted from

  • Wenzlau, J.M.; Garl, P.J.; Simpson, P.; Stenmark, K.R.; West, J.; Artinger, K.B.; Nemenoff, R.A.; Weiser-Evans, M.C.
    Embryonic growth-associated protein is one subunit of a novel N-terminal acetyltransferase complex essential for embryonic vascular development (2006), Circ. Res., 98, 846-855.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.256 expressed in HEK-293 cells Danio rerio

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.256 acetyl-CoA + an N-terminal-L-methionyl-L-isoleucyl-[protein] Danio rerio
-
 an N-terminal-Nalpha-acetyl-L-methionyl-L-isoleucyl-[protein] + CoA
-
 ?
2.3.1.256 acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[protein] Danio rerio
-
 an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[protein] + CoA
-
 ?
2.3.1.256 acetyl-CoA + an N-terminal-L-methionyl-L-phenylalanyl-[protein] Danio rerio
-
 an N-terminal-Nalpha-acetyl-L-methionyl-L-phenylalanyl-[protein] + CoA
-
 ?
2.3.1.256 acetyl-CoA + an N-terminal-L-methionyl-L-tryptophyl-[protein] Danio rerio
-
 an N-terminal-Nalpha-acetyl-L-methionyl-L-tryptophyl-[protein] + CoA
-
 ?
2.3.1.256 acetyl-CoA + an N-terminal-L-methionyl-L-tyrosinyl-[protein] Danio rerio
-
 an N-terminal-Nalpha-acetyl-L-methionyl-L-tyrosinyl-[protein] + CoA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.256 Danio rerio Q7T322
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.256 embryo
-
 Danio rerio
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.256 acetyl-CoA + an N-terminal-L-methionyl-L-isoleucyl-[protein]
-
 Danio rerio an N-terminal-Nalpha-acetyl-L-methionyl-L-isoleucyl-[protein] + CoA
-
 ?
2.3.1.256 acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[protein]
-
 Danio rerio an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[protein] + CoA
-
 ?
2.3.1.256 acetyl-CoA + an N-terminal-L-methionyl-L-phenylalanyl-[protein]
-
 Danio rerio an N-terminal-Nalpha-acetyl-L-methionyl-L-phenylalanyl-[protein] + CoA
-
 ?
2.3.1.256 acetyl-CoA + an N-terminal-L-methionyl-L-tryptophyl-[protein]
-
 Danio rerio an N-terminal-Nalpha-acetyl-L-methionyl-L-tryptophyl-[protein] + CoA
-
 ?
2.3.1.256 acetyl-CoA + an N-terminal-L-methionyl-L-tyrosinyl-[protein]
-
 Danio rerio an N-terminal-Nalpha-acetyl-L-methionyl-L-tyrosinyl-[protein] + CoA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.256 EGAP
-
 Danio rerio
2.3.1.256 embryonic growth-associated protein EGAP, subunit of the yeast NatC complex Danio rerio
2.3.1.256 MAK3
-
 Danio rerio
2.3.1.256 NatC
-
 Danio rerio

General Information

EC Number General Information Comment Organism
2.3.1.256 malfunction enzyme depletion results in severe cell growth defects and embryonic lethality Danio rerio
2.3.1.256 physiological function the enzyme is essential for embryonic development Danio rerio