EC Number | Cloned (Comment) | Organism |
---|---|---|
1.2.1.11 | expression Escherichia coli | Escherichia coli |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.2.1.11 | (S)-2-amino-5-fluoro-4-oxo-5-phosphono-pentanoic acid | irreversible inhibition | Escherichia coli | |
1.2.1.11 | (S)-2-amino-5-phosphono-pent-4-ynoic acid | - |
Escherichia coli | |
1.2.1.11 | acetylenic and z-olefinic analogues | competitive inhibition | Bacteria |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.1.11 | L-aspartate 4-semialdehyde + phosphate + NADP+ | Bacteria | - |
L-4-aspartyl phosphate + NADPH + H+ | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.2.1.11 | Bacteria | - |
- |
- |
1.2.1.11 | Escherichia coli | P0A9Q9 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.2.1.11 | to homogeneity | Escherichia coli |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.2.1.11 | cell culture | - |
Escherichia coli | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.1.11 | L-4-aspartyl phosphate + NADPH | - |
Escherichia coli | L-aspartate 4-semialdehyde + phosphate + NADP+ | - |
? | |
1.2.1.11 | L-aspartate 4-semialdehyde + phosphate + NADP+ | - |
Bacteria | L-4-aspartyl phosphate + NADPH + H+ | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.2.1.11 | ASA-DH | - |
Bacteria |
1.2.1.11 | ASA-DH | - |
Escherichia coli |
1.2.1.11 | aspartate semialdehyde dehydrogenase | - |
Escherichia coli |
1.2.1.11 | aspartate-semialdehyde dehydrogenase | - |
Bacteria |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.2.1.11 | NADP+ | - |
Bacteria | |
1.2.1.11 | NADPH | - |
Bacteria | |
1.2.1.11 | NADPH | - |
Escherichia coli |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.2.1.11 | 1.2 | - |
(S)-2-amino-5-fluoro-4-oxo-5-phosphono-pentanoic acid | 0.2 M Tris, 1 mM EDTA, pH 8.6, 15 mM phosphate, 0.15 mM NADP+, 37°C | Escherichia coli | |
1.2.1.11 | 3.9 | - |
(S)-2-amino-5-phosphono-pent-4-ynoic acid | 0.2 M Tris, 1 mM EDTA, pH 8.6, 15 mM phosphate, 0.15 mM NADP+, 37°C | Escherichia coli | |
1.2.1.11 | 20 | - |
z-olefin | - |
Bacteria |