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Literature summary extracted from

  • Stokes, A.J.; Shimoda, L.M.; Lee, J.W.; Rillero, C.; Chang, Y.; Turner, H.
    FceRI control of Ras via inositol (1,4,5) trisphosphate 3-kinase and inositol tetrakisphosphate (2006), Cell. Signal., 18, 640-651.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.127 ATP + 1D-myo-inositol 1,4,5-trisphosphate Rattus norvegicus InsP3K activity is a determinant of the extent of basal Ras activation in mast cells and of the Ras activation that follows antigenic crosslinking of the FcepsilonRI ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
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 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.127 Rattus norvegicus
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-
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.127 RBL-2H3 cell mast cell Rattus norvegicus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.127 ATP + 1D-myo-inositol 1,4,5-trisphosphate
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 Rattus norvegicus ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
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 ?
2.7.1.127 ATP + 1D-myo-inositol 1,4,5-trisphosphate InsP3K activity is a determinant of the extent of basal Ras activation in mast cells and of the Ras activation that follows antigenic crosslinking of the FcepsilonRI Rattus norvegicus ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.127 inositol (1,4,5) trisphosphate 3-kinase
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 Rattus norvegicus
2.7.1.127 InsP3K
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 Rattus norvegicus