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Literature summary extracted from

  • Liu, Y.; Borchert, G.L.; Donald, S.P.; Surazynski, A.; Hu, C.A.; Weydert, C.J.; Oberley, L.W.; Phang, J.M.
    MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells (2005), Carcinogenesis, 26, 1335-1342.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.5.1.2 medicine overexpression of proline oxidase causes apoptotic cell death in a variety of cancer cells Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.5.1.2 mitochondrial inner membrane
-
 Homo sapiens 5743
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.1.2 L-proline + NAD(P)+ Homo sapiens
-
 1-pyrroline-5-carboxylate + NAD(P)H + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.5.1.2 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.1.2 DLD-1 cell DLD-1 colorectal cancer cell Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.1.2 L-proline + NAD(P)+
-
 Homo sapiens 1-pyrroline-5-carboxylate + NAD(P)H + H+
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.5.1.2 POX
-
 Homo sapiens
1.5.1.2 proline oxidase
-
 Homo sapiens
1.5.1.2 pyrroline-5-carboxylate reductase
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.5.1.2 NAD(P)H
-
 Homo sapiens