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Literature summary extracted from

  • Thomas, R.M.; Toney, K.; Fenoglio-Preiser, C.; Revelo-Penafiel, M.P.; Hingorani, S.R.; Tuveson, D.A.; Waltz, S.E.; Lowy, A.M.
    The RON receptor tyrosine kinase mediates oncogenic phenotypes in pancreatic cancer cells and is increasingly expressed during pancreatic cancer progression (2007), Cancer Res., 67, 6075-6082.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.10.1 35000
-
 1 * 150000 + 1 * 35000 Mus musculus
2.7.10.1 35000
-
 1 * 150000 + 1 * 35000 Homo sapiens
2.7.10.1 150000
-
 1 * 150000 + 1 * 35000 Mus musculus
2.7.10.1 150000
-
 1 * 150000 + 1 * 35000 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.10.1 ATP + a [protein]-L-tyrosine Mus musculus
-
 ADP + a [protein]-L-tyrosine phosphate
-
 ?
2.7.10.1 ATP + a [protein]-L-tyrosine Homo sapiens
-
 ADP + a [protein]-L-tyrosine phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.10.1 Homo sapiens
-
-
-
2.7.10.1 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.10.1 AsPC-1 cell
-
 Homo sapiens
-
2.7.10.1 BxPC-3 cell
-
 Homo sapiens
-
2.7.10.1 CAPAN-1 cell
-
 Homo sapiens
-
2.7.10.1 HPAF-2 cell
-
 Homo sapiens
-
2.7.10.1 HS766T cell
-
 Homo sapiens
-
2.7.10.1 MiaPaCa-2 cell
-
 Homo sapiens
-
2.7.10.1 PANC-1 cell
-
 Homo sapiens
-
2.7.10.1 pancreatic cancer cell line
-
 Mus musculus
-
2.7.10.1 pancreatic cancer cell line
-
 Homo sapiens
-
2.7.10.1 pancreatic cancer cell line 4964LM cell Mus musculus
-
2.7.10.1 pancreatic cancer cell line 4964PDA cell Mus musculus
-
2.7.10.1 pancreatic cancer cell line 5143LM cell Mus musculus
-
2.7.10.1 pancreatic cancer cell line 5143PDA cell Mus musculus
-
2.7.10.1 PanIN cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.10.1 ATP + a [protein]-L-tyrosine
-
 Mus musculus ADP + a [protein]-L-tyrosine phosphate
-
 ?
2.7.10.1 ATP + a [protein]-L-tyrosine
-
 Homo sapiens ADP + a [protein]-L-tyrosine phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.10.1 heterodimer 1 * 150000 + 1 * 35000 Mus musculus
2.7.10.1 heterodimer 1 * 150000 + 1 * 35000 Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.7.10.1 recepteur d'origine nantais receptor tyrosine kinase
-
 Mus musculus
2.7.10.1 recepteur d'origine nantais receptor tyrosine kinase
-
 Homo sapiens
2.7.10.1 RON receptor tyrosine kinase
-
 Mus musculus
2.7.10.1 RON receptor tyrosine kinase
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.10.1 ATP
-
 Mus musculus
2.7.10.1 ATP
-
 Homo sapiens