EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.74 | additional information | enzyme protein level increases when cells are incubated with cyclopentenyl cytosine | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.74 | NTP + 2',2'-difluorodeoxycytidine | Homo sapiens | i.e. gemcitabine, rate limiting enzyme in the activation of the pharmaceutically relevant substrate which is commonly used in the treatment of solid malignant tumors | NDP + 2',2'-difluorodeoxycytidine 5'-phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.74 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.1.74 | SK-N-BE(2) cell | - |
Homo sapiens | - |
2.7.1.74 | SK-N-SH cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.74 | NTP + 2',2'-difluorodeoxycytidine | i.e. gemcitabine, rate limiting enzyme in the activation of the pharmaceutically relevant substrate which is commonly used in the treatment of solid malignant tumors | Homo sapiens | NDP + 2',2'-difluorodeoxycytidine 5'-phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.74 | dCK | - |
Homo sapiens |