Literature summary extracted from

Bourque, J.R.; Burley, R.K.; Bearne, S.L.
Intermediate analogue inhibitors of mandelate racemase: N-Hydroxyformanilide and cupferron (2007), Bioorg. Med. Chem. Lett., 17, 105-108.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
5.1.2.2	Cupferron	potent competitive inhibitor	Pseudomonas putida
5.1.2.2	N-hydroxyformanilide	potent competitive inhibitor, MR can bind either the protonated or deprotonated forms of N-hydroxyformanilide, with a 10fold greater affinity for the latter form	Pseudomonas putida

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
5.1.2.2	Mg2+	assay with 3.3 mM MgCl2	Pseudomonas putida

Organism

EC Number	Organism	UniProt	Comment	Textmining
5.1.2.2	Pseudomonas putida	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5.1.2.2	S-mandelate	-	Pseudomonas putida	R-mandelate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
5.1.2.2	mandelate racemase	-	Pseudomonas putida
5.1.2.2	MR	-	Pseudomonas putida

Temperature Optimum [°C]

EC Number	Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
5.1.2.2	25	-	assay at	Pseudomonas putida

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
5.1.2.2	7.5	-	assay at	Pseudomonas putida

Ki Value [mM]

EC Number	Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
5.1.2.2	0.00267	-	Cupferron	-	Pseudomonas putida
5.1.2.2	0.00279	-	N-hydroxyformanilide	-	Pseudomonas putida

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Release 2023.1 (January 2023)