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Literature summary extracted from

  • Valenti, D.; Vacca, R.A.; de Pinto, M.C.; De Gara, L.; Marra, E.; Passarella, S.
    In the early phase of programmed cell death in Tobacco Bright Yellow 2 cells the mitochondrial adenine nucleotide translocator, adenylate kinase and nucleoside diphosphate kinase are impaired in a reactive oxygen species-dependent manner (2007), Biochim. Biophys. Acta, 1767, 66-78.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.4.3 additional information after 2 h from heat-shock, when cell viability remains unaffected, the rate of ADP/ATP exchange due to adenine nucleotide translocator activity, and the activites of adenylate kinase and nucleoside diphosphate kinase are inhibited in a non-competitive like manner. Externally added ascorbate partially prevents inhibition Nicotiana tabacum
2.7.4.6 additional information heat shock causes a non-competitive inhibition of the enzyme, which is partly prevented by ascorbate, effects of heat shock on mitochondrial metabolism overview Nicotiana tabacum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.4.3 mitochondrion after 2 h from heat shock, rate of ADT/ATP exchange by adenine nucleotide translocator activity, adenylate kinase activity and nucleoside diphosphate kinase EC 2.7.4.6 are inhibitied in a non-competitive-like manner. Externally added ascorbate prevents the inhibition Nicotiana tabacum 5739
-
2.7.4.6 mitochondrial inner membrane NDPK is attached to the outer side of the inner the membrane Nicotiana tabacum 5743
-
2.7.4.6 mitochondrion after 2 h from heat shock, rate of ADT/ATP exchange by adenine nucleotide translocator activity, adenylate kinase activity EC 2.7.4.3 and nucleoside diphosphate kinase are inhibited in a non-competitive-like manner. Externally added ascorbate prevents the inhibition Nicotiana tabacum 5739
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.3 Nicotiana tabacum
-
-
-
2.7.4.3 Nicotiana tabacum
-
study on mitochondria during programmed cell death
-
2.7.4.6 Nicotiana tabacum
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study on mitochondria during programmed cell death
-
2.7.4.6 Nicotiana tabacum
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cv. Bright Yellow 2
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.4.6 native enzyme partially by mitochondrion preparation from protoplasts Nicotiana tabacum

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.4.3 TBY-2 cell
-
Nicotiana tabacum
-
2.7.4.3 TBY-2 cell non-photosynthetic cell Nicotiana tabacum
-
2.7.4.3 Tobacco Bright Yellow 2 cell
-
Nicotiana tabacum
-
2.7.4.6 TBY-2 cell
-
Nicotiana tabacum
-
2.7.4.6 TBY-2 cell i.e. Tobacco Bright Yellow 2 cells Nicotiana tabacum
-
2.7.4.6 Tobacco Bright Yellow 2 cell
-
Nicotiana tabacum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.6 ATP + CDP
-
Nicotiana tabacum ADP + CTP
-
r
2.7.4.6 ATP + TDP
-
Nicotiana tabacum ADP + TTP
-
r
2.7.4.6 ATP + UDP
-
Nicotiana tabacum ADP + UTP
-
r

Synonyms

EC Number Synonyms Comment Organism
2.7.4.6 NDPK
-
Nicotiana tabacum
2.7.4.6 nucleoside diphosphate kinase
-
Nicotiana tabacum