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Literature summary extracted from

  • Droese, S.; Galkin, A.; Brandt, U.
    Proton pumping by complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica reconstituted into proteoliposomes (2005), Biochim. Biophys. Acta, 1710, 87-95.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.1.1.2 9-amino-6-chloro-2-methoxyacridine 0.0005 mM Yarrowia lipolytica
7.1.1.2 carbonyl-cyanide-p-trifluoro-methoxy-phenylhydrazone 0.001 mM Yarrowia lipolytica
7.1.1.2 nigericin 0.0125 mM Yarrowia lipolytica
7.1.1.2 rotenone 0.001 mM Yarrowia lipolytica

Organism

EC Number Organism UniProt Comment Textmining
7.1.1.2 Yarrowia lipolytica
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
7.1.1.2 TSKgel 4000SW gel filtration Yarrowia lipolytica

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
7.1.1.2 4.1
-
 in 20 mM MOPS containing 50 mM KCl at pH 7.4, using n-decylubiquinone as substrate Yarrowia lipolytica
7.1.1.2 4.8
-
 in 20 mM MOPS containing 50 mM KCl at pH 7.4, using ubiquinone-1 as substrate Yarrowia lipolytica
7.1.1.2 39.1
-
 in 20 mM MOPS containing 50 mM KCl at pH 7.4, using hexamineruthenium(III)-chloride as substrate Yarrowia lipolytica

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.1.1.2 NADH + hexamineruthenium(III)-chloride
-
 Yarrowia lipolytica NAD+ + ?
-
 ?
7.1.1.2 NADH + n-decylubiquinone + H+
-
 Yarrowia lipolytica NAD+ + n-decylubiquinol
-
 ?
7.1.1.2 NADH + ubiquinone-1
-
 Yarrowia lipolytica NAD+ + ubiquinol-1
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.1.1.2 complex I
-
 Yarrowia lipolytica
7.1.1.2 NADH:ubiquinone oxidoreductase
-
 Yarrowia lipolytica

Cofactor

EC Number Cofactor Comment Organism Structure
7.1.1.2 NADH
-
 Yarrowia lipolytica