EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.99.1 | naproxen | inhibitor of cyclooxigenase reaction; inhibitor of cyclooxigenase reaction | Ovis aries |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.14.99.1 | microsome | - |
Ovis aries | - |
- |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.14.99.1 | 72000 | - |
monomer | Ovis aries |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.99.1 | arachidonate + AH2 + O2 | Ovis aries | - |
prostaglandin H2 + A + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.99.1 | Ovis aries | P05979 | PGHS-1 precursor | - |
1.14.99.1 | Ovis aries | P79208 | PGHS-2 precursor | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.99.1 | arachidonate + AH2 + O2 | - |
Ovis aries | prostaglandin H2 + A + H2O | - |
? | |
1.14.99.1 | arachidonic acid + 2 O2 | cyclooxygenase reaction, arachidonic acid as electron donor | Ovis aries | prostaglandin G2 | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.14.99.1 | homodimer | - |
Ovis aries |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.99.1 | PGHS | - |
Ovis aries |
1.14.99.1 | PGHS-1 | one of two isoforms found in mammalian cells, always present and provides their normal functioning | Ovis aries |
1.14.99.1 | PGHS-2 | one of two isoforms found in mammalian cells, produced in response to certain stimuli, such as cytokines and growth factors | Ovis aries |
1.14.99.1 | prostaglandin-endoperoxide synthase | - |
Ovis aries |
1.14.99.1 | prostaglandin-H-synthase | - |
Ovis aries |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.14.99.1 | 25 | - |
kinetic assay | Ovis aries |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.14.99.1 | 8 | - |
kinetic assay | Ovis aries |