Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Terry, K.L.; Casey, P.J.; Beese, L.S.
    Conversion of protein farnesyltransferase to a geranylgeranyltransferase (2006), Biochemistry, 45, 9746-9755.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.5.1.59 0.00000133
-
 Asp-Asp-Pro-Thr-Ala-Ser-Ala-Cys-Val-Leu-Leu at 30°C Homo sapiens
2.5.1.59 0.00003934
-
 geranylgeranyl diphosphate at 30°C Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.59 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.59
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.59 geranylgeranyl diphosphate + Asp-Asp-Pro-Thr-Ala-Ser-Ala-Cys-Val-Leu-Leu
-
 Homo sapiens Asp-Asp-Pro-Thr-Ala-Ser-Ala-(S-geranylgeranyl)-Cys-Val-Leu-Leu + diphosphate
-
 ?
2.5.1.59 geranylgeranyl diphosphate + protein-cysteine
-
 Homo sapiens S-geranylgeranyl-protein + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.59 PGGTase-I
-
 Homo sapiens
2.5.1.59 protein geranylgeranyltransferase type-I
-
 Homo sapiens

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.5.1.59 0.021
-
 geranylgeranyl diphosphate at 30°C Homo sapiens
2.5.1.59 0.021
-
 Asp-Asp-Pro-Thr-Ala-Ser-Ala-Cys-Val-Leu-Leu at 30°C Homo sapiens