Literature summary extracted from

Rabeh, W.M.; Alguindigue, S.S.; Cook, P.F.
Mechanism of the addition half of the O-acetylserine sulfhydrylase-A reaction (2005), Biochemistry, 44, 5541-5550.

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.5.1.47	Salmonella enterica subsp. enterica serovar Typhimurium	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.5.1.47	O-acetyl-L-Ser + H2S	the second half of the OASS-A reaction is limited by the conformational change needed to open the active site and release the amino acid product. No quinonoid or geminal-diamine intermediates are detected. The amino acid external Schiff base of the enzyme is found to be very stable when the reaction is run in D2O	Salmonella enterica subsp. enterica serovar Typhimurium	L-Cys + acetate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.5.1.47	OASS-A	-	Salmonella enterica subsp. enterica serovar Typhimurium

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Release 2023.1 (January 2023)