Literature summary extracted from

Steussy, C.N.; Vartia, A.A.; Burgner, J.W.; Sutherlin, A.; Rodwell, V.W.; Stauffacher, C.V.
X-ray crystal structures of HMG-CoA synthase from Enterococcus faecalis and a complex with its second substrate/inhibitor acetoacetyl-CoA (2005), Biochemistry, 44, 14256-14267.

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
2.3.3.10	unliganded and in complex with its second substrate/inhibitor acetoacetyl-CoA. The acetoacetyl-CoA binary structure demonstrates reduced coenzyme A and acetoacetate covalently bound to the active site cysteine through a thioester bond	Enterococcus faecalis

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.3.3.10	acetoacetyl-CoA	potent inhibitor of the overall reaction	Enterococcus faecalis

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.3.3.10	Enterococcus faecalis	-	-	-

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Release 2023.1 (January 2023)