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Literature summary extracted from

  • Sparks, J.D.; Collins, H.L.; Chirieac, D.V.; Cianci, J.; Jokinen, J.; Sowden, M.P.; Galloway, C.A.; Sparks, C.E.
    Hepatic very-low-density lipoprotein and apolipoprotein B production are increased following in vivo induction of betaine-homocysteine S-methyltransferase (2006), Biochem. J., 395, 363-371.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.1.1.5 betaine together with methionine restriction induces hepatic BHMT 4fold compared with methionine restriction alone, BHMT mRNAlevel is also increased by 3fold by betaine supplementation of methionine-replete diets Rattus norvegicus

Application

EC Number Application Comment Organism
2.1.1.5 additional information relationship between BHMT expression and ApoB mRNA in transfected McA cells recapitulated in vivo through dietary BHMT induction, providing additional support for a physiologic linkage between 1-carbon metabolism and apob gene expression Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.5 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.5 liver
-
 Rattus norvegicus
-

Synonyms

EC Number Synonyms Comment Organism
2.1.1.5 BHMT
-
 Rattus norvegicus