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Literature summary extracted from

  • Godber, B.L.; Schwarz, G.; Mendel, R.R.; Lowe, D.J.; Bray, R.C.; Eisenthal, R.; Harrison, R.
    Molecular characterization of human xanthine oxidoreductase: the enzyme is grossly deficient in molybdenum and substantially deficient in iron-sulphur centres (2005), Biochem. J., 388, 501-508.
    View publication on PubMedView publication on EuropePMC

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.17.1.4 Iron enzyme is about 30% deficient in iron-sulfur centers on basis of UV/vis and CD spectra Homo sapiens
1.17.1.4 Molybdenum 0.04 atoms per subunit Homo sapiens
1.17.1.4 Molybdenum 0.61 atoms per subunit Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.17.1.4 148000
-
 x * 148000, MALDI-TOF Homo sapiens
1.17.1.4 148300
-
 x * 148300, MALDI-TOF Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.17.1.4 additional information Bos taurus xanthine oxidoreductase plays a physiological role in milk equal in importance to its catalytic function as an enzyme ?
-
 ?
1.17.1.4 additional information Homo sapiens xanthine oxidoreductase plays a physiological role in milk equal in importance to its catalytic function as an enzyme ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.17.1.4 Bos taurus
-
-
-
1.17.1.4 Homo sapiens P47989
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.17.1.4 milk
-
 Bos taurus
-
1.17.1.4 milk
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.1.4 additional information xanthine oxidoreductase plays a physiological role in milk equal in importance to its catalytic function as an enzyme Bos taurus ?
-
 ?
1.17.1.4 additional information xanthine oxidoreductase plays a physiological role in milk equal in importance to its catalytic function as an enzyme Homo sapiens ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.17.1.4 ? x * 148000, MALDI-TOF Homo sapiens
1.17.1.4 ? x * 148300, MALDI-TOF Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
1.17.1.4 FAD 1 mol per mol of subunit Bos taurus
1.17.1.4 FAD 1 mol per mol of subunit Homo sapiens
1.17.1.4 molybdopterin 0.09 molecules per subunit Homo sapiens
1.17.1.4 molybdopterin 0.62 molecules per subunit Bos taurus