Literature summary extracted from

Zhao, Z.; Rothery, R.A.; Weiner, J.H.
Effects of site-directed mutations in Escherichia coli succinate dehydrogenase on the enzyme activity and production of superoxide radicals (2006), Biochem. Cell Biol., 84, 1013-1021.

Protein Variants

EC Number	Protein Variants	Comment	Organism
1.3.5.1	H71L	mutation significantly reduces the succinate-ubiquinone reductase activity of the enzyme, mutant enzyme produces more superoxide than the wild-type enzyme	Escherichia coli
1.3.5.1	H91L	mutant enzyme produces more superoxide than the wild-type enzyme	Escherichia coli
1.3.5.1	I28E	mutation significantly reduces the succinate-ubiquinone reductase activity of the enzyme, mutant enzyme produces more superoxide than the wild-type enzyme	Escherichia coli

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.3.5.1	Escherichia coli	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.3.5.1	succinate + ubiquinone	-	Escherichia coli	fumarate + ubiquinol	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.3.5.1	SdhCDAB	-	Escherichia coli

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.3.5.1	FAD	-	Escherichia coli

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Release 2023.1 (January 2023)