Literature summary extracted from

Hsu, M.; Muchova, L.; Morioka, I.; Wong, R.J.; Schroeder, H.; Stevenson, D.K.
Tissue-specific effects of statins on the expression of heme oxygenase-1 in vivo (2006), Biochem. Biophys. Res. Commun., 343, 738-744.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.14.14.18	Sn-protoporphyrin	0.001 mM, 84% inhibition of HO-1, 99% inhibition of HO-2	Rattus norvegicus
1.14.14.18	Zn-protoporphyrin	0.001 mM, 87% inhibition of HO-1, 91% inhibition of HO-2	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
1.14.14.18	microsome	-	Rattus norvegicus	-	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.14.18	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.14.14.18	testis	HO-1	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.14.18	heme + electron donor + O2	-	Rattus norvegicus	biliverdin + Fe2+ + CO + oxidized eletron donor + H2O	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.14.14.18	heme oxygenase-1	-	Rattus norvegicus
1.14.14.18	HO-1	-	Rattus norvegicus

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Release 2023.1 (January 2023)