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Literature summary extracted from

  • Anguera, M.C.; Stover, P.J.
    Methenyltetrahydrofolate synthetase is a high-affinity catecholamine-binding protein (2006), Arch. Biochem. Biophys., 455, 175-187.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
6.3.3.2 dopamine 0.02 mM, increases the initial rapid phase of folate turnover by 4% Mus musculus
6.3.3.2 additional information L-dopa does not affect folate turnover rate Mus musculus
6.3.3.2 N-acetyldopamine 0.02 mM, accelerates markedly folate turnover Mus musculus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.3.2 expressed in Escherichia coli BL21 Star cells and MCF-7 cells Mus musculus
6.3.3.2 expressed in Escherichia coli BL21 Star cells and MCF-7 cells Oryctolagus cuniculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.3.3.2 25210
-
 calculated from amino acid sequence Mus musculus
6.3.3.2 25220
-
 MALDI-TOF Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
6.3.3.2 Mus musculus
-
-
-
6.3.3.2 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.3.2 liver
-
 Mus musculus
-
6.3.3.2 liver
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.3.2 ATP + 5-formyltetrahydrofolate
-
 Mus musculus ADP + 5,10-methenyltetrahydrofolate + phosphate
-
 ?
6.3.3.2 ATP + 5-formyltetrahydrofolate
-
 Oryctolagus cuniculus ADP + 5,10-methenyltetrahydrofolate + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.3.3.2 Methenyltetrahydrofolate synthetase
-
 Mus musculus
6.3.3.2 Methenyltetrahydrofolate synthetase
-
 Oryctolagus cuniculus
6.3.3.2 MTHFS
-
 Mus musculus
6.3.3.2 MTHFS
-
 Oryctolagus cuniculus