EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.7.43 | Co2+ | - |
Rattus norvegicus | |
2.7.7.43 | Cu2+ | - |
Rattus norvegicus | |
2.7.7.43 | DTT | in the presence of 0.01 M DTT enzyme shows 20% activity loss | Rattus norvegicus | |
2.7.7.43 | Hg2+ | - |
Rattus norvegicus | |
2.7.7.43 | Mn2+ | - |
Rattus norvegicus | |
2.7.7.43 | additional information | enzyme is inhibited by thiol-modifying reagents; enzyme is not inhibited by thiol-containing reagents like GSH, mercaptoethanol and cysteine | Rattus norvegicus | |
2.7.7.43 | NaF | in the presence of 0.06 M NaF enzyme shows 17% activity loss | Rattus norvegicus | |
2.7.7.43 | Sn2+ | - |
Rattus norvegicus | |
2.7.7.43 | Zn2+ | - |
Rattus norvegicus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.7.7.43 | 46000 | - |
- |
Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.7.43 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.7.43 | by column chromatography on Sephacryl S-200 (gel filtration), Yellow-86-Agarose (affinity) and Phenyl-Sepharose (hydrophobic affinity) | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.7.43 | brain | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.43 | CTP + N-acetyl-neuraminic acid | - |
Rattus norvegicus | CMP-Neu5Ac + diphosphate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.7.7.43 | tetramer | 4*190000, gel filtration | Rattus norvegicus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.7.43 | CMP-Neu5Ac synthetase | - |
Rattus norvegicus |
2.7.7.43 | N-Acetyl-neuraminic acid cytidylyltransferase | - |
Rattus norvegicus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.7.7.43 | 40 | - |
greatest activity is observed at 40°C | Rattus norvegicus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.7.7.43 | 9 | - |
- |
Rattus norvegicus |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
2.7.7.43 | 8.5 | 9.5 | - |
Rattus norvegicus |