EC Number | Application | Comment | Organism |
---|---|---|---|
6.5.1.2 | analysis | high-throughput assay for the adenylation reaction of bacterial DNA ligase | Escherichia coli |
EC Number | Cloned (Comment) | Organism |
---|---|---|
6.5.1.2 | - |
Escherichia coli |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.5.1.2 | 2-methylthio ADP | - |
Escherichia coli | |
6.5.1.2 | 2-methylthio-ATP | - |
Escherichia coli | |
6.5.1.2 | ADP | inhibits adenylation reaction | Escherichia coli | |
6.5.1.2 | AMP | inhibits adenylation reaction | Escherichia coli | |
6.5.1.2 | ATP | inhibits adenylation reaction | Escherichia coli | |
6.5.1.2 | cAMP | inhibits adenylation reaction | Escherichia coli | |
6.5.1.2 | Rp-cAMPS | - |
Escherichia coli | |
6.5.1.2 | Sp-cAMPS | - |
Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.5.1.2 | Escherichia coli | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
6.5.1.2 | - |
Escherichia coli |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
6.5.1.2 | 0.0011 | - |
37°C, pH 7.4, DNA ligation | Escherichia coli | 2-methylthio ATP | |
6.5.1.2 | 0.0015 | - |
37°C, pH 7.4, DNA ligation | Escherichia coli | Sp-3',5'-cyclic adenosine monophosphothiolate | |
6.5.1.2 | 0.0041 | - |
37°C, pH 7.4, DNA ligation | Escherichia coli | 2-methylthio ADP | |
6.5.1.2 | 0.12 | - |
37°C, pH 7.4, DNA ligation | Escherichia coli | (Rp)-3',5'-cyclic adenosine monophosphothiolate |