EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.1 | S-nitrosoglutathione | hexokinase is particularly susceptible to protein structure modifications when exposed to even low concentrations of S-nitrosoglutathione. Biologically relevant [S-nitrosoglutathione]/[hexokinase] causes a significant decrease in Vmax with glucose (but not with fructose), along with oxidation of 5 Met and nitration of 4 Tyr. Preincubation of hexokinase with glucose abrogates the effect of S-nitrosoglutathione whereas fructose is ineffective | Saccharomyces cerevisiae |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.1 | 0.3 | - |
D-glucose | S-nitrosoglutathione treated enzyme | Saccharomyces cerevisiae | |
2.7.1.1 | 0.47 | - |
D-glucose | - |
Saccharomyces cerevisiae | |
2.7.1.1 | 2.9 | - |
D-fructose | - |
Saccharomyces cerevisiae | |
2.7.1.1 | 2.9 | - |
D-fructose | S-nitrosoglutathione treated enzyme | Saccharomyces cerevisiae |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.1 | Saccharomyces cerevisiae | P04806 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.1 | ATP + D-fructose | - |
Saccharomyces cerevisiae | ADP + D-fructose 6-phosphate | - |
? | |
2.7.1.1 | ATP + D-glucose | - |
Saccharomyces cerevisiae | ADP + D-glucose 6-phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.1 | hexokinase A | - |
Saccharomyces cerevisiae |
2.7.1.1 | HXK A | - |
Saccharomyces cerevisiae |
EC Number | Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|---|
2.7.1.1 | Saccharomyces cerevisiae | - |
- |
5.3 |