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Literature summary extracted from

  • Li, J.X.; Pang, Y.Z.; Tang, C.S.; Li, Z.Q.
    Protective effect of taurine on hypochlorous acid toxicity to nuclear nucleoside triphosphatase in isolated nuclei from rat liver (2004), World J. Gastroenterol., 10, 694-698.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.6.1.15 taurine activates the enzyme, and acts as antagonist and reduces the hypochlorous acid toxicity Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.15 HOCl inhibits the muclear NTPase, taurine acts as antagonist and reduces the hypochlorous acid toxicity Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.6.1.15 nucleus nuclear envelope Rattus norvegicus 5634
-

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.15 Rattus norvegicus
-
 male sprague-dawley rats
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.6.1.15 partially, isolation of hepatic nuclei Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.1.15 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.15 ATP + H2O
-
 Rattus norvegicus ADP + phosphate
-
 ?
3.6.1.15 GTP + H2O preferred substrate Rattus norvegicus GDP + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.6.1.15 NTPase
-
 Rattus norvegicus
3.6.1.15 nucleoside triphosphatase
-
 Rattus norvegicus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.6.1.15 30
-
 assay at Rattus norvegicus