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Literature summary extracted from

  • Lu, H.; Zhu, J.; Zang, Y.; Ze, Y.; Qin, J.
    Cloning, purification, and refolding of human paraoxonase-3 expressed in Escherichia coli and its characterization (2006), Protein Expr. Purif., 46, 92-99.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.2 expression in Escherichia coli Homo sapiens
3.1.1.25 expression in Escherichia coli Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.2 7.47
-
 phenyl acetate pH 8.0, 37°C Homo sapiens
3.1.1.25 0.83
-
 phenyl acetate pH 8.0, 37°C Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.2 40000
-
 x * 40000, SDS-PAGE Homo sapiens
3.1.1.25 40000
-
 x * 40000, SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.2 Homo sapiens Q15166
-
-
3.1.1.25 Homo sapiens Q15166
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.2
-
 Homo sapiens
3.1.1.25
-
 Homo sapiens

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.2 15
-
-
 Homo sapiens
3.1.1.25 212
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.2 additional information rhPON3 can effectively delay and inhibit oxidation of high density lipoprotein in vitro Homo sapiens ?
-
 ?
3.1.1.2 phenyl acetate + H2O
-
 Homo sapiens phenol + acetate
-
 ?
3.1.1.25 dihydrocoumarin + H2O
-
 Homo sapiens 3-(2-hydroxyphenyl)propanoic acid
-
 ?
3.1.1.25 additional information rhPON3 can effectively delay and inhibit oxidation of high density lipoprotein in vitro Homo sapiens ?
-
 ?
3.1.1.25 phenyl acetate + H2O
-
 Homo sapiens ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.2 ? x * 40000, SDS-PAGE Homo sapiens
3.1.1.25 ? x * 40000, SDS-PAGE Homo sapiens