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Literature summary extracted from

  • Lee, J.H.; Lee, S.Y.; Lee, K.S.; Jang, H.J.; Lee, K.H.; Hahn, T.R.; Paik, Y.S.
    Prolyl endopeptidase inhibitors from the leaves of Ginkgo biloba (2004), Planta Med., 70, 1228-1230.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.26 6-(10Z-heptadecenyl)salicylic acid isolated from leaves of Ginkgo biloba, noncompetitive, 50% inhibition at 0.00062 mM Elizabethkingia meningoseptica
3.4.21.26 6-(8Z-pentadecenyl)salicylic acid isolated from leaves of Ginkgo biloba, noncompetitive, 50% inhibition at 0.00086 mM Elizabethkingia meningoseptica
3.4.21.26 oleic acid 50% inhibition at 0.031 mM Elizabethkingia meningoseptica
3.4.21.26 salicylic acid 50% inhibition at 1.65 mM Elizabethkingia meningoseptica
3.4.21.26 Z-L-Pro-prolinal 50% inhibition at 0.0000022 mM Elizabethkingia meningoseptica

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.26 Elizabethkingia meningoseptica
-
 commercial preparation
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.26 benzyloxycarbonyl-Gly-L-Pro-4-nitroanilide + H2O
-
 Elizabethkingia meningoseptica ?
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.4.21.26 0.0008
-
 6-(10Z-heptadecenyl)salicylic acid pH 7.0, 37°C Elizabethkingia meningoseptica
3.4.21.26 0.00087
-
 6-(8Z-pentadecenyl)salicylic acid pH 7.0, 37°C Elizabethkingia meningoseptica