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Literature summary extracted from
- Unexpected stereorecognition in nitrilase-catalyzed hydrolysis of beta-hydroxy nitriles (2006), Org. Lett., 8, 4429-4431.
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.5.1 | Bradyrhizobium japonicum | - |
USDA110 | - |
| 3.5.5.1 | Bradyrhizobium japonicum USDA 110 | - |
USDA110 | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.5.1 | 3-(2,4-dichlorophenyl)-3-hydroxypropanenitrile + H2O | nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles | Bradyrhizobium japonicum | (S)-3-(2,4-dichlorophenyl)-3-hydroxypropanoic acid + NH3 | - |
? |  |
| 3.5.5.1 | 3-(2,4-dichlorophenyl)-3-hydroxypropanenitrile + H2O | nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles | Bradyrhizobium japonicum USDA 110 | (S)-3-(2,4-dichlorophenyl)-3-hydroxypropanoic acid + NH3 | - |
? | |
| 3.5.5.1 | 3-(2-chlorophenyl)-3-hydroxypropanenitrile + H2O | nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles | Bradyrhizobium japonicum | 3-(2-chlorophenyl)-3-hydroxypropanoic acid + NH3 | - |
? | |
| 3.5.5.1 | 3-(2-chlorophenyl)-3-hydroxypropanenitrile + H2O | nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles | Bradyrhizobium japonicum USDA 110 | 3-(2-chlorophenyl)-3-hydroxypropanoic acid + NH3 | - |
? | |
| 3.5.5.1 | 3-(4-chlorophenyl)-3-hydroxypropanenitrile + H2O | nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles | Bradyrhizobium japonicum | (S)-3-(4-chlorophenyl)-3-hydroxypropanoic acid + NH3 | - |
? | |
| 3.5.5.1 | 3-(4-chlorophenyl)-3-hydroxypropanenitrile + H2O | nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles | Bradyrhizobium japonicum USDA 110 | (S)-3-(4-chlorophenyl)-3-hydroxypropanoic acid + NH3 | - |
? | |
| 3.5.5.1 | 3-(4-fluorophenyl)-3-hydroxypropanenitrile + H2O | nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles | Bradyrhizobium japonicum | (S)-3-(4-fluorophenyl)-3-hydroxypropanoic acid + NH3 | - |
? | |
| 3.5.5.1 | 3-(4-fluorophenyl)-3-hydroxypropanenitrile + H2O | nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles | Bradyrhizobium japonicum USDA 110 | (S)-3-(4-fluorophenyl)-3-hydroxypropanoic acid + NH3 | - |
? | |
| 3.5.5.1 | 3-hydroxy-3-(2-methoxyphenyl)propanenitrile + H2O | nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles | Bradyrhizobium japonicum | (S)-3-hydroxy-3-(2-methoxyphenyl)propanoic acid + NH3 | - |
? | |
| 3.5.5.1 | 3-hydroxy-3-(2-methoxyphenyl)propanenitrile + H2O | nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles | Bradyrhizobium japonicum USDA 110 | (S)-3-hydroxy-3-(2-methoxyphenyl)propanoic acid + NH3 | - |
? | |
| 3.5.5.1 | 3-hydroxy-3-(3-methoxyphenyl)propanenitrile + H2O | nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles | Bradyrhizobium japonicum | (S)-3-hydroxy-3-(3-methoxyphenyl)propanoic acid + NH3 | - |
? | |
| 3.5.5.1 | 3-hydroxy-3-(4-methoxyphenyl)propanenitrile + H2O | nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles | Bradyrhizobium japonicum | (S)-3-hydroxy-3-(4-methoxyphenyl)propanoic acid + NH3 | - |
? | |
| 3.5.5.1 | 3-hydroxy-3-(4-methylphenyl)propanenitrile + H2O | nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles | Bradyrhizobium japonicum | (S)-3-hydroxy-3-(4-methylphenyl)propanoic acid + NH3 | - |
? | |
| 3.5.5.1 | 3-hydroxy-3-phenylpropanenitrile + H2O | nitrilase bll6402 catalyzes the enantioselective hydrolysis of aromatic beta-hydroxy nitriles to give (S)-enriched beta-hydroxy carboxylic acids with recovery of (R)-enriched beta-hydroxy nitriles | Bradyrhizobium japonicum | (S)-3-hydroxy-3-phenylpropanoic acid + NH3 | - |
? | |
| 3.5.5.1 | hydroxy(phenyl)acetonitrile + H2O | hydrolysis of alpha-hydroxynitriles is not enantioselective | Bradyrhizobium japonicum | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.5.5.1 | nitrilase bll6402 | - |
Bradyrhizobium japonicum |
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